1H-Isoindole-1,3(2H)-dione, 2-[2-[(4-aminophenyl)thio]ethyl]-

Base Information

Chemical Name:1H-Isoindole-1,3(2H)-dione, 2-[2-[(4-aminophenyl)thio]ethyl]-
CAS No.:147591-62-6
Molecular Formula:C16H14N2O2S
Molecular Weight:298.365
Hs Code.:
DSSTox Substance ID:DTXSID60349806
Wikidata:Q82125289
ChEMBL ID:CHEMBL1539124
Mol file:147591-62-6.mol

Synonyms:147591-62-6;SMR000043387;MLS000080870;1H-Isoindole-1,3(2H)-dione, 2-[2-[(4-aminophenyl)thio]ethyl]-;2-[2-(4-aminophenyl)sulfanylethyl]isoindole-1,3-dione;regid861439;Oprea1_715846;cid_662683;CHEMBL1539124;BDBM37377;DTXSID60349806;HMS2410L07;STK365311;AKOS003749778;2-[2-[(4-aminophenyl)thio]ethyl]isoindole-1,3-dione;2-(2-((4-Aminophenyl)thio)ethyl)isoindoline-1,3-dione;2-[2-[(4-aminophenyl)thio]ethyl]isoindoline-1,3-quinone;2-{2-[(4-aminophenyl)sulfanyl]ethyl}-1H-isoindole-1,3(2H)-dione

Suppliers and Price of 1H-Isoindole-1,3(2H)-dione, 2-[2-[(4-aminophenyl)thio]ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 1H-Isoindole-1,3(2H)-dione, 2-[2-[(4-aminophenyl)thio]ethyl]-

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:298.07759887
Heavy Atom Count:21
Complexity:383

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)CCSC3=CC=C(C=C3)N

Technology Process of 1H-Isoindole-1,3(2H)-dione, 2-[2-[(4-aminophenyl)thio]ethyl]-

There total 3 articles about 1H-Isoindole-1,3(2H)-dione, 2-[2-[(4-aminophenyl)thio]ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 147591-61-5
4-nitrophenyl 2-(N-phthalimidoyl)ethyl sulfide

: 147591-62-6
p-(2-phthalimidoethylthio)aniline

Guidance literature:: With hydrogen; nickel; In diethylene glycol dimethyl ether; at 100 ℃; for 0.5h; under 76000 Torr;
DOI:10.1007/BF00529476

Reference yield:

: 574-98-1
2-(2-bromoethyl)isoindoline-1,3-dione

: 147591-62-6
p-(2-phthalimidoethylthio)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / C₅H₁₁ONa / pentan-1-ol / 8 h / 130 °C

2: 80 percent / H₂ / Raney nickel / bis-(2-methoxy-ethyl) ether / 0.5 h / 100 °C / 76000 Torr

With C₅H₁₁ONa; hydrogen; nickel; In pentan-1-ol; diethylene glycol dimethyl ether;
DOI:10.1007/BF00529476

Reference yield:

: 1849-36-1
para-nitrobenzenethiol

: 147591-62-6
p-(2-phthalimidoethylthio)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / C₅H₁₁ONa / pentan-1-ol / 8 h / 130 °C

2: 80 percent / H₂ / Raney nickel / bis-(2-methoxy-ethyl) ether / 0.5 h / 100 °C / 76000 Torr

With C₅H₁₁ONa; hydrogen; nickel; In pentan-1-ol; diethylene glycol dimethyl ether;
DOI:10.1007/BF00529476