sodium pyridine-2-acetate

Base Information

• Chemical Name: sodium pyridine-2-acetate
• CAS No.: 67870-16-0
• Molecular Formula: C7H7 N O2 . Na
• Molecular Weight: 159.12
• Hs Code.: 2933399090
• Mol file: 67870-16-0.mol

Synonyms:2-Pyridineaceticacid, sodium salt (9CI); Sodium 2-pyridineacetate; Sodium 2-pyridylacetate

Chemical Property of sodium pyridine-2-acetate

Chemical Property:

• Vapor Pressure: 0.00235mmHg at 25°C
• Boiling Point: 276.2°C at 760 mmHg
• Flash Point: 120.8°C
• PSA: 53.02000
• LogP: -0.62600
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

Sodium 2-(pyridin-2-yl)acetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of sodium pyridine-2-acetate

There total 2 articles about sodium pyridine-2-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-(pyridinyl-2)acetate (2739-98-2) → pyridin-2-yl-acetic acid; sodium salt (67870-16-0)

Guidance literature:

With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/acsmedchemlett.0c00335

Reference yield:

pyridin-2-yl acetic acid hydrochloride (16179-97-8) → pyridin-2-yl-acetic acid; sodium salt (67870-16-0)

Guidance literature:

With sodium ethanolate; In ethanol;

DOI:10.1016/0022-328X(95)06105-6

Reference yield: 9.0%

trans-N1-(6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-yl)-N4-methylcyclohexane-1,4-diamine (1388890-16-1) + pyridin-2-yl-acetic acid; sodium salt (67870-16-0) → N-methyl-2-(pyridin-2-yl)-N-[4-([7-thia-9,11-diazatricyclo[6.4.0.0(2,6)]dodeca-1(8),2(6),9,11-tetraen-12-yl]amino)cyclohexyl]acetamide (1388891-26-6)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 50 ℃; for 5h;

upstream raw materials:

pyridin-2-yl acetic acid hydrochloride

ethyl 2-(pyridinyl-2)acetate

Downstream raw materials:

7-acetoxy-3-(2-pyridinyl)-2H-1-benzopyran-2-one

N-methyl-2-(pyridin-2-yl)-N-[4-([7-thia-9,11-diazatricyclo[6.4.0.0(2,6)]dodeca-1⁽⁸⁾,2⁽⁶⁾,9,11-tetraen-12-yl]amino)cyclohexyl]acetamide