3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE

Base Information

• Chemical Name: 3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE
• CAS No.: 14944-26-4
• Molecular Formula: C16H14O
• Molecular Weight: 222.287
• Mol file: 14944-26-4.mol

Synonyms:3-Phenyl-3,4-dihydro-2H-naphthalin-1-on;4-Oxo-2-phenyl-tetralin;3-phenyl-1,2,3,4-tetrahydro-1-naphthalenone;3-phenyl-3,4-dihydronaphthalen-1(2H)-one;3-phenyl-3,4-dihydro-2H-naphthalen-1-one;4-Oxo-2-phenyl-1.2.3.4-tetrahydro-naphthalin;1(2H)-Naphthalenone, 3,4-dihydro-3-phenyl-;

Chemical Property of 3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE

Chemical Property:

• PSA: 17.07000
• LogP: 3.59930

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE

There total 32 articles about 3-PHENYL-3,4-DIHYDRO-1(2H)-NAPHTHALENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3-benzyl-3-phenylpropionic acid (4374-49-6) → 3-phenyl-1-tetralone (14944-26-4)

Guidance literature:

With polyphosphoric acid; at 120 ℃; for 3h;

DOI:10.1039/d0ob01848a

Reference yield: 58.0%

2-(2-phenylallyl)benzaldehyde (1325230-39-4) → 3-phenyl-1-tetralone (14944-26-4)

Guidance literature:

2-(2-phenylallyl)benzaldehyde; With chlorobis(cyclooctene)rhodium(I) dimer; 3-methyl-5-(pyrrolidin-1-yl)pyridin-2-amine; aniline; triphenylphosphine; benzoic acid; In 4-methyl-1,2,3-trifluorobenzene; at 100 ℃; for 15h; Inert atmosphere;

With hydrogenchloride; In dichloromethane; water; 4-methyl-1,2,3-trifluorobenzene; for 0.166667h;

DOI:10.1021/jo300779q

Reference yield: 53.0%

C16H12O → 3-phenyl-1-tetralone (14944-26-4)

Guidance literature:

With triethylsilane; di(rhodium)tetracarbonyl dichloride; In dichloromethane; at 0 - 20 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c9nj02954k

upstream raw materials:

2-Iodo-3-phenyl-1,2,3,4-tetrahydro-naphthalene

3-benzyl-3-phenylpropionic acid

bromobenzene

1-Phenylbut-1-en-3-one

Downstream raw materials:

2-phenyltetralin

3-Phenyl-tetralol-1

1-(hydroxyimino)-3-phenyl-1,2,3,4-tetrahydronaphthalene

3-phenyl-1-tetralone-2,2-d₂