Adenosine, N-benzoyl-, 2',3'-dibenzoate

Base Information

• Chemical Name: Adenosine, N-benzoyl-, 2',3'-dibenzoate
• CAS No.: 14985-43-4
• Molecular Formula: C31H25N5O7
• Molecular Weight: 579.569
• Mol file: 14985-43-4.mol

Synonyms:N6-benzoyl-9-(2',3'-di-O-benzoyl-β-D-ribofuranosyl)adenine;6-N-Benzoyl-2',3'-di-O-benzoyladenosine;N6,O2',O3'-tribenzoyladenosine;N6,2',3'-O-tribenzoyl-D-adenosine;N6,O2',O3'-tribenzoyl-adenosine;

Chemical Property of Adenosine, N-benzoyl-, 2',3'-dibenzoate

Chemical Property:

• PSA: 154.76000
• Density: 1.45±0.1 g/cm3(Predicted)
• LogP: 3.49250

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Adenosine, N-benzoyl-, 2',3'-dibenzoate

There total 5 articles about Adenosine, N-benzoyl-, 2',3'-dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C50H41N5O7 → N-benzoyl-2',3'-di-O-benzoyladenosine (14985-43-4)

Guidance literature:

With chlorine; In chloroform; at 4 ℃; for 0.5h;

DOI:10.1080/00397919408019048

Reference yield:

C52H43N5O9 (133465-48-2) → N-benzoyl-2',3'-di-O-benzoyladenosine (14985-43-4)

Guidance literature:

With benzenesulfonic acid; In methanol; at 0 ℃; for 15h;

DOI:10.1016/j.tetasy.2005.07.026

Reference yield:

6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine (129666-75-7,81246-82-4) → N-benzoyl-2',3'-di-O-benzoyladenosine (14985-43-4)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine; 4-(dimethylamino)pyridine / CH₂Cl₂ / 1 h / 20 °C

2: 3.96 g / benzenesulfonic acid / methanol / 15 h / 0 °C

With dmap; triethylamine; benzenesulfonic acid; In methanol; dichloromethane;

DOI:10.1016/j.tetasy.2005.07.026

upstream raw materials:

C₅₂H₄₃N₅O₉

6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)adenosine

N-benzoyladenosine

Downstream raw materials:

C₈₂H₇₄ClN₈O₂₀P

C₈₃H₇₁ClN₁₁O₁₈P

C₈₂H₇₁ClN₉O₁₈P

C₈₅H₇₁ClN₉O₁₈P