4-[4-(4-Hydroxyphenoxy)phenoxy]phenol

Base Information

• Chemical Name: 4-[4-(4-Hydroxyphenoxy)phenoxy]phenol
• CAS No.: 15051-26-0
• Molecular Formula: C18H14O4
• Molecular Weight: 294.307
• DSSTox Substance ID: DTXSID00354898
• Nikkaji Number: J357.645K
• Wikidata: Q82133381
• ChEMBL ID: CHEMBL1549870
• Mol file: 15051-26-0.mol

Synonyms:MLS001162917;15051-26-0;4,4'-[1,4-phenylenebis(oxy)]diphenol;SMR000495822;4,4'-(1,4-Phenylenebis(oxy))diphenol;4-[4-(4-hydroxyphenoxy)phenoxy]phenol;HMS1578P03;Phenol, 4,4'-[1,4-phenylenebis(oxy)]bis-;CBChromo1_000119;Oprea1_843631;CBDivE_012255;SCHEMBL249169;cid_786365;CHEMBL1549870;BDBM53447;DTXSID00354898;HMS2829M11;O-acyl oxime isatin derivative, 13;AKOS016402779;4-[4-(4-oxidanylphenoxy)phenoxy]phenol;MLS-0348143.0001

Chemical Property of 4-[4-(4-Hydroxyphenoxy)phenoxy]phenol

Chemical Property:

• XLogP3: 4.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 294.08920892
• Heavy Atom Count: 22
• Complexity: 279

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1O)OC2=CC=C(C=C2)OC3=CC=C(C=C3)O

Technology Process of 4-[4-(4-Hydroxyphenoxy)phenoxy]phenol

There total 15 articles about 4-[4-(4-Hydroxyphenoxy)phenoxy]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.8%

4,4'-(1,4-phenylenebis(oxy))bis(4,1-phenylene) diacetate (83743-89-9) → 4,4'-(1,4-phenylenebis(oxy)) diphenol (15051-26-0)

Guidance literature:

With methanol; potassium hydroxide; for 1h; Reflux;

Reference yield: 91.0%

1,4-bis(p-methoxyphenoxyl)benzene (78563-40-3) → 4,4'-(1,4-phenylenebis(oxy)) diphenol (15051-26-0)

Guidance literature:

With hydrogen iodide; acetic acid;

DOI:10.1080/00397910008087313

Reference yield: 76.0%

4,4'[1,4-phenylenebis(oxy)]bisphenol diformate (126045-63-4) → 4,4'-(1,4-phenylenebis(oxy)) diphenol (15051-26-0)

Guidance literature:

With potassium hydroxide; In methanol; for 1h; Heating;

DOI:10.1055/s-1991-26381

upstream raw materials:

1,4-bis(p-methoxyphenoxyl)benzene

4,4'[1,4-phenylenebis(oxy)]bisphenol diformate

4,4'-(1,4-phenylenebis(oxy))bis(4,1-phenylene) diacetate

1.4-dibromobenzene

Downstream raw materials:

4-[4-(4-Dodecyloxy-phenoxy)-phenoxy]-phenol

C₃₄H₄₅BrO₄

(4-{4-[4-(4-Dodecyloxy-phenoxy)-phenoxy]-phenoxy}-butyl)-trimethyl-ammonium; bromide

2-[4-[4-[4-(1-carboxy-ethoxy)-phenoxy]phenoxy]-phenoxy]-propionic acid