3,5-Cyclohexadiene-1,2-diol, 3-iodo-6-methyl-, (1S,2S)-

Base Information

Chemical Name:3,5-Cyclohexadiene-1,2-diol, 3-iodo-6-methyl-, (1S,2S)-
CAS No.:150895-41-3
Molecular Formula:C7H9IO2
Molecular Weight:252.052
Hs Code.:
Mol file:150895-41-3.mol

Synonyms:

Suppliers and Price of 3,5-Cyclohexadiene-1,2-diol, 3-iodo-6-methyl-, (1S,2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 3,5-Cyclohexadiene-1,2-diol, 3-iodo-6-methyl-, (1S,2S)-

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3,5-Cyclohexadiene-1,2-diol, 3-iodo-6-methyl-, (1S,2S)-

There total 1 articles about 3,5-Cyclohexadiene-1,2-diol, 3-iodo-6-methyl-, (1S,2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 624-31-7
4-tolyl iodide

: 150895-41-3
(1S,2S)-1,2-dihydroxy-3-methyl-6-iodo-cyclohexa-3,5-diene

: (1R,2R)-3-Iodo-6-methyl-cyclohexa-3,5-diene-1,2-diol

Guidance literature:: With water; oxygen; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Pseudomonas putida UV₄;
DOI:10.1039/c39930000974

Reference yield:

: 150895-41-3
(1S,2S)-1,2-dihydroxy-3-methyl-6-iodo-cyclohexa-3,5-diene

: 154333-41-2
cis-1,2-dihydrocatechol

Guidance literature:: With hydrogen; sodium acetate; palladium on activated charcoal; In methanol; under 760 Torr; Yield given; Ambient temperature;

Reference yield:

: 150895-41-3
(1S,2S)-1,2-dihydroxy-3-methyl-6-iodo-cyclohexa-3,5-diene

: C₂₁H₂₈O₄

: C₂₁H₂₈O₄

Guidance literature:: Multi-step reaction with 11 steps

1.1: p-toluenesulfonic acid monohydrate / 0.25 h / 0 °C

2.1: tert.-butyl lithium; zinc(II) iodide / diethyl ether; pentane; tetrahydrofuran / 1 h / -78 - 18 °C

2.2: 18 h / 18 °C / Enzymatic reaction

3.1: 2,6-di-tert-butyl-4-methyl-phenol / toluene / 20 h / 112 °C / Reflux

4.1: water / methanol / 48 h / 70 °C

5.1: dmap / pyridine / 48 h / 18 °C

6.1: dimethyl sulfoxide; oxalyl dichloride; triethylamine / dichloromethane / 0.99 h / -78 °C

7.1: samarium diiodide / tetrahydrofuran; methanol / 0.08 h / -78 °C

8.1: dichloromethane / 13 h / 18 °C / Irradiation

9.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / -78 °C

10.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 24 h / 40 °C

11.1: water; osmium(VIII) oxide; 4-methylmorpholine N-oxide; iso-butanol / acetone / 24 h / 18 °C

With dmap; osmium(VIII) oxide; lithium aluminium tetrahydride; samarium diiodide; oxalyl dichloride; 2,6-di-tert-butyl-4-methyl-phenol; p-toluenesulfonic acid monohydrate; water; tert.-butyl lithium; dimethyl sulfoxide; 4-methylmorpholine N-oxide; triethylamine; triphenylphosphine; iso-butanol; zinc(II) iodide; diethylazodicarboxylate; In tetrahydrofuran; pyridine; methanol; diethyl ether; dichloromethane; acetone; toluene; pentane; 2.2: |Negishi Coupling / 3.1: |Diels-Alder Cycloaddition / 6.1: |Swern Oxidation / 10.1: |Mitsunobu Displacement / 11.1: |Upjohn Dihydroxylation;
DOI:10.1021/ol5034817