Chloro-acetic acid (2R,3R,4S,5R,6R)-3-acetoxy-4,5-bis-benzyloxy-6-((1R,2R,3S,4R,5R)-3,4-bis-benzyloxy-6,8-dioxa-bicyclo[3.2.1]oct-2-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Base Information

• Chemical Name: Chloro-acetic acid (2R,3R,4S,5R,6R)-3-acetoxy-4,5-bis-benzyloxy-6-((1R,2R,3S,4R,5R)-3,4-bis-benzyloxy-6,8-dioxa-bicyclo[3.2.1]oct-2-yloxy)-tetrahydro-pyran-2-ylmethyl ester
• CAS No.: 115435-53-5
• Molecular Formula: C₄₄H₄₇ClO₁₂
• Molecular Weight: 803.303
• Mol file: 115435-53-5.mol

Synonyms:

Chemical Property of Chloro-acetic acid (2R,3R,4S,5R,6R)-3-acetoxy-4,5-bis-benzyloxy-6-((1R,2R,3S,4R,5R)-3,4-bis-benzyloxy-6,8-dioxa-bicyclo[3.2.1]oct-2-yloxy)-tetrahydro-pyran-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Chloro-acetic acid (2R,3R,4S,5R,6R)-3-acetoxy-4,5-bis-benzyloxy-6-((1R,2R,3S,4R,5R)-3,4-bis-benzyloxy-6,8-dioxa-bicyclo[3.2.1]oct-2-yloxy)-tetrahydro-pyran-2-ylmethyl ester

There total 1 articles about Chloro-acetic acid (2R,3R,4S,5R,6R)-3-acetoxy-4,5-bis-benzyloxy-6-((1R,2R,3S,4R,5R)-3,4-bis-benzyloxy-6,8-dioxa-bicyclo[3.2.1]oct-2-yloxy)-tetrahydro-pyran-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-(2,3,6-tri-O-benzyl-α-D-glucopyranosyl)-(1->4)-bis4)>-2,3,6-tri-O-benzyl-β-D-glucopyranoside (113842-97-0) + O-(4-O-acetyl-2,3-di-O-benzyl-6-O-monochloroacetyl-α-D-glucopyranosyl-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranosyl fluoride (115435-52-4) → Chloro-acetic acid (2R,3R,4S,5R,6R)-3-acetoxy-4,5-bis-benzyloxy-6-((1R,2R,3S,4R,5R)-3,4-bis-benzyloxy-6,8-dioxa-bicyclo[3.2.1]oct-2-yloxy)-tetrahydro-pyran-2-ylmethyl ester (115435-53-5) + Chloro-acetic acid (2R,3R,4S,5R,6R)-3-acetoxy-4,5-bis-benzyloxy-6-((2R,3R,4S)-4,5-bis-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyran-3-yloxy)-tetrahydro-pyran-2-ylmethyl ester (115435-54-6) + allyl O-(4-O-acetyl-2,3-di-O-benzyl-6-O-monochloroacetyl-α-D-glucopyranosyl)-(1->4)-O-(2,3,6-tri-O-benzyl-β-D-glucopyranosyl-<(1->4)-O-(2,3,6-tri-O-benzyl-α-D-glucopyranosyl>3-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside (115435-55-7,115435-56-8) + allyl O-(4-O-acetyl-2,3-di-O-benzyl-6-O-monochloroacetyl-α-D-glucopyranosyl)-<(1->4)-O-(2,3,6-tri-O-benzyl-α-D-glucopyranosyl>4-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside (115435-55-7,115435-56-8)

Guidance literature:

With 4 A molecular sieve; silver trifluoromethanesulfonate; tin(ll) chloride; Yield given. Multistep reaction. Yields of byproduct given; 1) Cl(CH₂)2Cl, 20 deg C, 16 h, 2) Cl(CH₂)2Cl, 20 deg C, 19 h;

DOI:10.1016/0008-6215(87)80246-X

upstream raw materials:

O-(2,3,6-tri-O-benzyl-α-D-glucopyranosyl)-(1->4)-bis4)>-2,3,6-tri-O-benzyl-β-D-glucopyranoside

O-(4-O-acetyl-2,3-di-O-benzyl-6-O-monochloroacetyl-α-D-glucopyranosyl-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranosyl fluoride