1H-Indole-2,3-dione, 1-[(2-nitrophenyl)methyl]-

Base Information

Chemical Name:1H-Indole-2,3-dione, 1-[(2-nitrophenyl)methyl]-
CAS No.:151383-69-6
Molecular Formula:C15H10N2O4
Molecular Weight:282.25100
Hs Code.:
DSSTox Substance ID:DTXSID60367000
Wikidata:Q82152543
ChEMBL ID:CHEMBL602429
Mol file:151383-69-6.mol

Synonyms:GNF-Pf-4753;1H-Indole-2,3-dione, 1-[(2-nitrophenyl)methyl]-;151383-69-6;CHEMBL602429;SCHEMBL18954615;DTXSID60367000;STK805334;AKOS000245096;1-(2-nitrobenzyl)-1H-indole-2,3-dione;1-[(2-nitrophenyl)methyl]indoline-2,3-dione;SR-01000277371;SR-01000277371-1

Suppliers and Price of 1H-Indole-2,3-dione, 1-[(2-nitrophenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of 1H-Indole-2,3-dione, 1-[(2-nitrophenyl)methyl]-

Chemical Property:

PSA：83.20000
LogP:2.91250
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:282.06405680
Heavy Atom Count:21
Complexity:459

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CN2C3=CC=CC=C3C(=O)C2=O)[N+](=O)[O-]

Technology Process of 1H-Indole-2,3-dione, 1-[(2-nitrophenyl)methyl]-

There total 4 articles about 1H-Indole-2,3-dione, 1-[(2-nitrophenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 151383-63-0
N-(o-nitrobenzyl)-oxanilic acid

: 151383-69-6
1-(2-Nitro-benzyl)-1H-indole-2,3-dione

Guidance literature:: With phosphorus pentachloride; In tetrachloromethane; for 12h; Ambient temperature;

Reference yield:

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 3958-60-9
2-nitrophenylmethyl bromide

: 151383-69-6
1-(2-Nitro-benzyl)-1H-indole-2,3-dione

Guidance literature:: With potassium carbonate; potassium iodide; In acetonitrile; at 20 ℃; for 4h;
DOI:10.1016/j.bmc.2004.02.005

Reference yield:

: 88-72-2
1-methyl-2-nitrobenzene

: 151383-69-6
1-(2-Nitro-benzyl)-1H-indole-2,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: N-bromosuccinimide; benzoyl peroxide / CCl₄ / 12 h / Heating

2: 1.39 g / potassium carbonate; potassium iodide / acetonitrile / 4 h / 20 °C

With N-Bromosuccinimide; potassium carbonate; potassium iodide; dibenzoyl peroxide; In tetrachloromethane; acetonitrile;
DOI:10.1016/j.bmc.2004.02.005