(2R,3S)-2-hydroxy-3-methylbutanedioic acid

Base Information

Chemical Name:(2R,3S)-2-hydroxy-3-methylbutanedioic acid
CAS No.:152204-30-3
Molecular Formula:C5H8O5
Molecular Weight:148.116
Hs Code.:
DSSTox Substance ID:DTXSID001344281
Nikkaji Number:J883.007J
Wikidata:Q27103106
Metabolomics Workbench ID:51299
ChEMBL ID:CHEMBL226414
Mol file:152204-30-3.mol

Synonyms:D-erythro-3-methylmalic acid;(2R,3S)-2-hydroxy-3-methylbutanedioic acid;(2R,3S)-3-methylmalic acid;152204-30-3;(2R,3S)-3-Methylmalate;CHEBI:27394;D-erythro-3-Methylmalate;(2R,3S)-2-hydroxy-3-methylsuccinic acid;CHEMBL226414;SCHEMBL2251200;NPYQJIHHTGFBLN-STHAYSLISA-N;DTXSID001344281;AKOS006380144;C06032;Q27103106

Suppliers and Price of (2R,3S)-2-hydroxy-3-methylbutanedioic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (2R,3S)-2-hydroxy-3-methylbutanedioic acid

Chemical Property:

XLogP3:-0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:148.03717335
Heavy Atom Count:10
Complexity:152

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(C(=O)O)O)C(=O)O
Isomeric SMILES:C[C@@H]([C@H](C(=O)O)O)C(=O)O

Technology Process of (2R,3S)-2-hydroxy-3-methylbutanedioic acid

There total 4 articles about (2R,3S)-2-hydroxy-3-methylbutanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 498-23-7,7407-59-2
citraconic acid

: 6236-10-8,2306-22-1
(R)-(-)-citramalic acid

: 152204-30-3,5380-36-9,5380-37-0
(2R,3S)-3-methylmalic acid

Guidance literature:: With TETRACYCLINE; In water; at 37 ℃; for 142h; Title compound not separated from byproducts; Clostridium formicoaceticum, phosphate buffer;
DOI:10.1016/S0040-4020(01)85678-7

Reference yield:

: 874646-35-2
diisopropyl (2S,3R)-2-methyl-3-hydroxybutanedioate

: diisopropyl (2R,3R)-2-methyl-3-hydroxybutanedioate

: 152204-30-3,5380-36-9,5380-37-0
(2R,3S)-3-methylmalic acid

: 13398-40-8,5380-36-9,5380-37-0
(2R,3R)-threo-β-methylmalic acid

Guidance literature:: diisopropyl (2S,3R)-2-methyl-3-hydroxybutanedioate; diisopropyl (2R,3R)-2-methyl-3-hydroxybutanedioate; With potassium hydroxide; water; In tetrahydrofuran; at 0 - 20 ℃; for 48h;

With hydrogenchloride; In water;