2-(4-ETHYL-PHENOXY)-PROPIONIC ACID ETHYL ESTER

Base Information

• Chemical Name: 2-(4-ETHYL-PHENOXY)-PROPIONIC ACID ETHYL ESTER
• CAS No.: 153472-88-9
• Molecular Formula: C₁₃H₁₈O₃
• Molecular Weight: 222.284
• Mol file: 153472-88-9.mol

Synonyms:2-(4-Ethyl-phenoxy)-propionic acid ethyl ester;ethyl 2-(4-ethylphenoxy)propionate;

Chemical Property of 2-(4-ETHYL-PHENOXY)-PROPIONIC ACID ETHYL ESTER

Chemical Property:

• PSA: 35.53000
• LogP: 2.57940

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-ETHYL-PHENOXY)-PROPIONIC ACID ETHYL ESTER

There total 1 articles about 2-(4-ETHYL-PHENOXY)-PROPIONIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-Ethyl potassium phenolate (75121-14-1) + Ethyl 2-bromopropionate (535-11-5,41978-69-2) → (R/S)-Ethyl 2-(4-ethylphenoxy)propionate (153472-88-9)

Guidance literature:

Reference yield:

(R/S)-Ethyl 2-(4-ethylphenoxy)propionate (153472-88-9) + butan-1-ol (71-36-3) → ethyl (R)-2-(4-ethylphenoxy)propionate (154004-93-0) + (R)-Butyl 2-(4-ethylphenoxy)propionate (197158-47-7) + (S)-Butyl 2-(4-ethylphenoxy)propionate (197158-51-3) + ethyl (S)-2-(4-ethylphenoxy)propionate

Guidance literature:

With Bacillus licheniformis serine protease; In 2,2,4-trimethylpentane; dimethyl sulfoxide; at 37 ℃;

DOI:10.1016/j.bioorg.2004.05.001

Reference yield:

(R/S)-Ethyl 2-(4-ethylphenoxy)propionate (153472-88-9) + butan-1-ol (71-36-3) → Butyl 2-(4-ethylphenoxy)propionate (308087-12-9)

Guidance literature:

subtilisin; In 2,2,4-trimethylpentane; dimethyl sulfoxide; at 37 ℃; Kinetics;

DOI:10.1039/b101269j

upstream raw materials:

p-Ethyl potassium phenolate

Ethyl 2-bromopropionate

Downstream raw materials:

(+/-)-2-(4-ethylphenoxy)propanoic acid

Butyl 2-(4-ethylphenoxy)propionate

ethyl (R)-2-(4-ethylphenoxy)propionate

(R)-Butyl 2-(4-ethylphenoxy)propionate