(3-Methoxyphenyl)hydrazine

Base Information

• Chemical Name: (3-Methoxyphenyl)hydrazine
• CAS No.: 15384-39-1
• Molecular Formula: C7H10N2O
• Molecular Weight: 138.169
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID801311307
• Nikkaji Number: J264.801F
• Mol file: 15384-39-1.mol

Synonyms:(3-methoxyphenyl)hydrazine;15384-39-1;(3-methoxy-phenyl)-hydrazine;Hydrazine, (3-methoxyphenyl)-;m-methoxyphenylhydrazine;3-methoxyphenylhydrazine;EINECS 254-368-4;1-(3-Methoxyphenyl)hydrazine;3-Methoxyphenyl hydrazine;(3-methoxyphenyl)-hydrazine;(3'-methoxyphenyl)-hydrazine;Hydrazine,(3-methoxyphenyl)-;SCHEMBL719275;1-(3-Methoxyphenyl)hydrazine #;DTXSID801311307;STK503801;AKOS000200821;NSC 155337;BB 0241892

Chemical Property of (3-Methoxyphenyl)hydrazine

Chemical Property:

• Melting Point: 59-60 °C
• Boiling Point: 275℃
• PKA: 5.41±0.10(Predicted)
• Flash Point: 120℃
• PSA: 47.28000
• Density: 1.150
• LogP: 1.75410
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 138.079312947
• Heavy Atom Count: 10
• Complexity: 97.6

Purity/Quality:

99% ^*data from raw suppliers

(3-Methoxyphenyl)hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC(=C1)NN

Technology Process of (3-Methoxyphenyl)hydrazine

There total 6 articles about (3-Methoxyphenyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

m-Anisidine (536-90-3,918666-97-4) → (3-methoxyphenyl)hydrazine (15384-39-1)

Guidance literature:

With sodium hydroxide; sodium nitrate; stannous chloride; In hydrogenchloride; water;

Reference yield:

3-methoxyphenyl 4-methylbenzenesulfonate (3899-92-1) → (3-methoxyphenyl)hydrazine (15384-39-1)

Guidance literature:

With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; N-[2-(di(1-adamantyl)phosphino)phenyl]morpholine; hydrazine hydrate; sodium t-butanolate; In toluene; at 65 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/anie.201003764

Reference yield:

tin(II)chloride dihydrate + m-Anisidine (536-90-3,918666-97-4) → (3-methoxyphenyl)hydrazine (15384-39-1)

Guidance literature:

With sodium nitrite; In hydrogenchloride; sulfuric acid; water;

upstream raw materials:

m-Anisidine

m-methoxyphenylhydrazine hydrochloride

3-methoxyphenyl 4-methylbenzenesulfonate

1-chloro-3-methoxy-benzene

Downstream raw materials:

5-bromo-1-(3-methoxy-phenyl)-1H-indazole

C₁₄H₁₆N₂O₃S