8-amino-N-[8-({8-[(8-hydrazinyl-8-oxooctyl)amino]-8-oxooctyl}amino)-8-oxooctyl]octanamide

Base Information

Chemical Name:8-amino-N-[8-({8-[(8-hydrazinyl-8-oxooctyl)amino]-8-oxooctyl}amino)-8-oxooctyl]octanamide
CAS No.:86459-08-7
Molecular Formula:2BrH*C₃₂H₆₄N₆O₄
Molecular Weight:758.722
Hs Code.:

Synonyms:Octanoicacid, 8-[[8-[[8-[(8-amino-1-oxooctyl)amino]-1-oxooctyl]amino]-1-oxooctyl]amino]-,hydrazide, dihydrobromide (9CI); NSC 373690

Suppliers and Price of 8-amino-N-[8-({8-[(8-hydrazinyl-8-oxooctyl)amino]-8-oxooctyl}amino)-8-oxooctyl]octanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 8-amino-N-[8-({8-[(8-hydrazinyl-8-oxooctyl)amino]-8-oxooctyl}amino)-8-oxooctyl]octanamide

Chemical Property:

Vapor Pressure:2.42E-31mmHg at 25°C
Boiling Point:878°C at 760 mmHg
Flash Point:484.8°C
Density:1.015g/cm³

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-amino-N-[8-({8-[(8-hydrazinyl-8-oxooctyl)amino]-8-oxooctyl}amino)-8-oxooctyl]octanamide

There total 8 articles about 8-amino-N-[8-({8-[(8-hydrazinyl-8-oxooctyl)amino]-8-oxooctyl}amino)-8-oxooctyl]octanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 86459-07-6
35-benzyloxycarbonylamino-10,19,28-trioxo-9,18,27-triazapentatriacontanohydrazide

: 86459-08-7
35-amino-10,19,28-trioxo-9,18,27-triazapentatriacontanohydrazide dihydrobromide

Guidance literature:: With hydrogen bromide; acetic acid; for 2h;
DOI:10.1248/cpb.31.737

Reference yield:

: 1074-51-7
cyclooctanone oxime

: 86459-08-7
35-amino-10,19,28-trioxo-9,18,27-triazapentatriacontanohydrazide dihydrobromide

Guidance literature:: Multi-step reaction with 6 steps

2: 89 percent / Et₃N, DMAP, DCC / CH₂Cl₂ / 24 h / 0 - 20 °C

3: 84 percent / 0.5N NaOH / acetone; H₂O / 24 h / Ambient temperature

4: 84 percent / Et₃N, isobutyl chlorocarbonate / dimethylformamide; tetrahydrofuran / -18 - 25 °C

5: hydrazine hydrate / methanol / Heating

6: 98 percent / 25percent HBr/AcOH / 2 h

With dmap; sodium hydroxide; hydrogen bromide; hydrazine hydrate; acetic acid; triethylamine; dicyclohexyl-carbodiimide; isobutyl chloroformate; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetone;
DOI:10.1248/cpb.31.737

Reference yield:

: 23434-40-4
8-(benzyloxycarbonylamino)octanoic acid

: 86459-08-7
35-amino-10,19,28-trioxo-9,18,27-triazapentatriacontanohydrazide dihydrobromide

Guidance literature:: Multi-step reaction with 5 steps

1: 89 percent / Et₃N, DMAP, DCC / CH₂Cl₂ / 24 h / 0 - 20 °C

2: 84 percent / 0.5N NaOH / acetone; H₂O / 24 h / Ambient temperature

3: 84 percent / Et₃N, isobutyl chlorocarbonate / dimethylformamide; tetrahydrofuran / -18 - 25 °C

4: hydrazine hydrate / methanol / Heating

5: 98 percent / 25percent HBr/AcOH / 2 h

With dmap; sodium hydroxide; hydrogen bromide; hydrazine hydrate; acetic acid; triethylamine; dicyclohexyl-carbodiimide; isobutyl chloroformate; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetone;
DOI:10.1248/cpb.31.737