2,3,6-Trichloroaniline

Base Information

• Chemical Name: 2,3,6-Trichloroaniline
• CAS No.: 88963-39-7
• Molecular Formula: C₆H₄Cl₃N
• Molecular Weight: 196.463
• Mol file: 88963-39-7.mol

Synonyms:Aniline,2,3,6-trichloro- (6CI,7CI); 2,3,6-Trichloroaniline

Chemical Property of 2,3,6-Trichloroaniline

Chemical Property:

• Vapor Pressure: 0.0116mmHg at 25°C
• Melting Point: 63-64 °C
• Boiling Point: 261.4°C at 760 mmHg
• PKA: -0.35±0.10(Predicted)
• Flash Point: 111.9°C
• PSA: 26.02000
• Density: 1.54g/cm³
• LogP: 3.81020
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

2,3,6-Trichloroaniline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,3,6-Trichloroaniline

There total 10 articles about 2,3,6-Trichloroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2',3',6'-Trichlorobenzanilide (88963-38-6) → 2,3,6-trichloroanisole (88963-39-7)

Guidance literature:

With sulfuric acid; for 3h; Heating;

Reference yield:

1,2,4-trichloro-3-nitrobenzene (27864-13-7) → 2,3,6-trichloroanisole (88963-39-7)

Guidance literature:

With hydrogenchloride; iron; at 70 ℃;

Reference yield:

N-(2,5-dichloro-phenyl)-hydroxylamine (43192-05-8) → 2,3,6-trichloroanisole (88963-39-7)

Guidance literature:

Multi-step reaction with 3 steps

1: NaHCO₃ / diethyl ether; H₂O / 1 h / T < 5 deg C; or in benzene

2: 77 percent / SOCl₂ / diethyl ether / 1 h / T < 5 deg C

3: 65 percent / 70percent H₂SO₄ / 3 h / Heating

With thionyl chloride; sulfuric acid; sodium hydrogencarbonate; In diethyl ether; water;

upstream raw materials:

1,2,4-trichloro-3-nitrobenzene

2',3',6'-Trichlorobenzanilide

4-Amino-2.3.5-trichlor-phenyl-sulfonsaeure-amid

N-(2,5-dichloro-phenyl)-hydroxylamine

Downstream raw materials:

bis-(2,3,6-trichloro-phenyl)-disulfide

2,3,6-trichlorobiphenyl

2,3,6-trichloro-5-nitro-aniline

acetic acid-(2,3,6-trichloro-5-nitro-anilide)