Mesoprazine

Base Information

• Chemical Name: Mesoprazine
• CAS No.: 1824-09-5
• Molecular Formula: C10H18 Cl N5 O
• Molecular Weight: 259.739
• Hs Code.: 2933699090
• European Community (EC) Number: 955-413-7
• UNII: X8902D4L2K
• DSSTox Substance ID: DTXSID10171290
• Nikkaji Number: J9.533H
• Wikidata: Q27293678
• Mol file: 1824-09-5.mol

Synonyms:Mesoprazine;1824-09-5;Mesoprazine [ISO];6-chloro-4-N-(3-methoxypropyl)-2-N-propan-2-yl-1,3,5-triazine-2,4-diamine;UNII-X8902D4L2K;X8902D4L2K;G 34698;2-Chloro-4-isopropylamino-6-(3-methoxypropylamino)-1,3,5-triazine;6-Chloro-N-(3-methoxypropyl)-N'-(1-methylethyl)-1,3,5-triazine-2,4-diamine;1,3,5-Triazine-2,4-diamine, 6-chloro-N-(3-methoxypropyl)-N'-(1-methylethyl)-;C10H18ClN5O;SCHEMBL135999;C10-H18-Cl-N5-O;DTXSID10171290;Mesoprazine 100 microg/mL in Acetonitrile;Q27293678;s-Triazine, 2-chloro-4-(isopropylamino)-6-[(3-methoxypropyl)amino]-;6-CHLORO-N(SUP 2)-ISOPROPYL-N(SUP 4)-(3-METHOXYPROPYL)-1,3,5-TRIAZINE-2,4-DIAMINE

Chemical Property of Mesoprazine

Chemical Property:

• Boiling Point: 418.2oC at 760 mmHg
• Flash Point: 206.7oC
• PSA: 78.42000
• Density: 1.241g/cm3
• LogP: 0.63750
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 259.1199879
• Heavy Atom Count: 17
• Complexity: 207

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)NC1=NC(=NC(=N1)NCCCOC)Cl
• Uses: Mesoprazine is a reagent in the palladium-catalyzed thiomethylation reaction.

Technology Process of Mesoprazine

There total 1 articles about Mesoprazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6-chloro-N2-isopropyl-N4-(3-methoxypropyl)-1,3,5-triazine-2,4-diamine (1824-09-5)

Guidance literature:

Cyanurchlorid, Isopropylamin, MeO(CH2)3NH2;

Reference yield: 97.0%

6-chloro-N2-isopropyl-N4-(3-methoxypropyl)-1,3,5-triazine-2,4-diamine (1824-09-5) + carbonic acid dimethyl ester (616-38-6) → 2-Methylmercapto-4-isopropylamino-6-(3-methoxypropylamino)-s-triazine (841-06-5)

Guidance literature:

With potassium tert-butylate; palladium diacetate; triphenylphosphine; potassium thioacetate; In dimethyl sulfoxide; at 120 ℃; Inert atmosphere;

Downstream raw materials:

2-Methylmercapto-4-isopropylamino-6-(3-methoxypropylamino)-s-triazine