4-[(4-Methylpiperazine-1-)sulfonyl]aniline

Base Information

• Chemical Name: 4-[(4-Methylpiperazine-1-)sulfonyl]aniline
• CAS No.: 21623-68-7
• Molecular Formula: C11H17N3O2S
• Molecular Weight: 255.341
• Hs Code.: 29335990
• Mol file: 21623-68-7.mol

Synonyms:Piperazine,1-[(4-aminophenyl)sulfonyl]-4-methyl- (9CI);Piperazine, 1-methyl-4-sulfanilyl-(8CI);4-(4'-Sulfanilyl)-1-methylpiperazine;4-[(4-Methyl-1-piperazinyl)sulfonyl]aniline;

Chemical Property of 4-[(4-Methylpiperazine-1-)sulfonyl]aniline

Chemical Property:

• Vapor Pressure: 2.12E-07mmHg at 25°C
• Melting Point: 228-229 °C
• Boiling Point: 424.1 °C at 760 mmHg
• PKA: 6.38±0.42(Predicted)
• Flash Point: 210.3 °C
• PSA: 75.02000
• Density: 1.289 g/cm³
• LogP: 1.74270
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

4-(4-Methylpiperazine-1-sulfonyl)aniline 98.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-[(4-Methylpiperazine-1-)sulfonyl]aniline

There total 11 articles about 4-[(4-Methylpiperazine-1-)sulfonyl]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-methyl-4-((4-nitrophenyl)sulphonyl)-piperazine → 4-(4-methyl-piperazine-1-sulfonyl)-aniline (21623-68-7)

Guidance literature:

Reference yield: 99.0%

→ 4-(4-methyl-piperazine-1-sulfonyl)-aniline (21623-68-7)

Guidance literature:

Reference yield: 92.0%

N-[4-(4-Methylpiperazine-1-sulfonyl)phenyl]acetamide (88858-84-8) → 4-(4-methyl-piperazine-1-sulfonyl)-aniline (21623-68-7)

Guidance literature:

With hydrogenchloride; water; In methanol; for 1h; Reflux;

DOI:10.3390/molecules23123152

upstream raw materials:

N-[4-(4-Methylpiperazine-1-sulfonyl)phenyl]acetamide

1-methyl-piperazine

p-acetylaminobenzenesulfonyl chloride

1,4-dioxane

Downstream raw materials:

N-(4-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-3-oxobenzo[d]isothiazole-2(3H)-carboxamide