Technology Process of 4H-1-Benzopyran-4-one,
5,6,8-trimethoxy-2-[4-methoxy-3-(phenylmethoxy)phenyl]-7-(phenylmeth
oxy)-
There total 14 articles about 4H-1-Benzopyran-4-one,
5,6,8-trimethoxy-2-[4-methoxy-3-(phenylmethoxy)phenyl]-7-(phenylmeth
oxy)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 150 ℃;
for 0.0833333h;
DOI:10.1246/bcsj.69.1033
- Guidance literature:
-
Multi-step reaction with 13 steps
1: pyridine
2: 77 percent / K2CO3 / acetone; dimethylformamide / 50 h / Heating
3: 10percent aq. NaOH / methanol / 0.5 h / Ambient temperature
4: K2CO3 / acetone / 3 h / Heating
5: H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature
6: pyridine
7: 1.) AcOH, BF3(g), 2.) pyridine / 1.) from 50 to 60 deg C, 5 h
8: 10percent aq. NaOH / methanol / 0.25 h / Ambient temperature
9: (i-Pr)2NEt / CH2Cl2 / 0.83 h / 5 °C
10: pyridine / 3 h / 60 - 70 °C
11: KOH, pyridine / 2 h / 60 °C
12: conc. H2SO4, HOAc / 1 h / 50 °C
13: 90 percent / K2CO3 / dimethylformamide / 0.08 h / 150 °C
With
pyridine; potassium hydroxide; sodium hydroxide; sulfuric acid; boron trifluoride; hydrogen; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine;
palladium on activated charcoal;
In
methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetone;
DOI:10.1246/bcsj.69.1033
- Guidance literature:
-
Multi-step reaction with 12 steps
1: 77 percent / K2CO3 / acetone; dimethylformamide / 50 h / Heating
2: 10percent aq. NaOH / methanol / 0.5 h / Ambient temperature
3: K2CO3 / acetone / 3 h / Heating
4: H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature
5: pyridine
6: 1.) AcOH, BF3(g), 2.) pyridine / 1.) from 50 to 60 deg C, 5 h
7: 10percent aq. NaOH / methanol / 0.25 h / Ambient temperature
8: (i-Pr)2NEt / CH2Cl2 / 0.83 h / 5 °C
9: pyridine / 3 h / 60 - 70 °C
10: KOH, pyridine / 2 h / 60 °C
11: conc. H2SO4, HOAc / 1 h / 50 °C
12: 90 percent / K2CO3 / dimethylformamide / 0.08 h / 150 °C
With
pyridine; potassium hydroxide; sodium hydroxide; sulfuric acid; boron trifluoride; hydrogen; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine;
palladium on activated charcoal;
In
methanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetone;
DOI:10.1246/bcsj.69.1033
