(R)-tert-butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate

Base Information Edit

Chemical Name:(R)-tert-butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate
CAS No.:95715-87-0
Molecular Formula:C11H19NO4
Molecular Weight:229.276
Hs Code.:29349990
European Community (EC) Number:627-510-1
UNII:UPK623LV60
DSSTox Substance ID:DTXSID70914847
Nikkaji Number:J329.940F
Wikidata:Q27291189
Mol file:95715-87-0.mol

Synonyms:95715-87-0;(R)-tert-butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate;(R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde;tert-butyl (4R)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate;(R)-Garner Aldehyde;(R)-Garner's aldehyde;tert-Butyl (R)-(+)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate;Garner's aldehyde R-form [MI];(R)-4-Formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester;UNII-UPK623LV60;3-Oxazolidinecarboxylic acid, 4-forMyl-2,2-diMethyl-, 1,1-diMethylethyl ester, (4R)-;UPK623LV60;MFCD00674064;3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde, (R)-(+)-;(+)-tert-Butyl 4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate;(R)-tert-Butyl 4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate;(R)-4-Formyl-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester;(4R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine;Garner aldehyde;SCHEMBL209164;(R)-3-Boc-4-formyl-2,2-dimethyl-1,3-oxazolidine;(R)-(-)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde;DTXSID70914847;AMY19841;CS-D1111;tert-butyl (4R)-4-formyl-2,2-dimethyl-oxazolidine-3-carboxylate;AKOS015900623;DS-13083;EN300-177025;(4R)-2,2-Dimethyl-1,3-oxazolidine-4-carboxaldehyde;Q27291189;Z1505697190;(R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde, 95%;(R)-tert-Butyl-4-Formyl-2,2-dimethyl-3-oxazolidinecarboxylate;tert-butyl-(R)-4-formyl-2,2-dimethyl-3-oxazolidine-carboxylate;(R)-TERT-BUTYL4-FORMYL-2,2-DIMETHYLOXAZOLIDINE-3-CARBOXYLATE;(r)4-formyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester;1,1-dimethylethyl (R,S)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate;tert-Butyl(4R)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate;(4R)-4-Formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylic Acid tert-Butyl Ester;2-Methyl-2-propanyl (4R)-4-formyl-2,2-dimethyl-1,3-oxazolidine-3-carboxylate;3-Oxazolidinecarboxylic acid,4-forMyl-2,2-diMethyl-,1,1-diMethylethyl ester,(4R)-;(+)-N-Boc-N,O-isopropylidene-D-serinal, tert-Butyl (R)-(+)-4-formyl-2,2-dimethyl-3-oxazolidinecarboxylate

Suppliers and Price of (R)-tert-butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine
2g
$ 445.00

SynQuest Laboratories
(R)-N-Boc-4-formyl-2,2-dimethyl-oxazolidine 95%
5 g
$ 549.00

SynQuest Laboratories
(R)-N-Boc-4-formyl-2,2-dimethyl-oxazolidine 95%
1 g
$ 164.00

Sigma-Aldrich
(R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde 95%
1g
$ 98.00

Matrix Scientific
(R)-tert-Butyl4-formyl-2,2-dimethyloxazolidine-3-carboxylate 97%
5g
$ 267.00

Crysdot
(R)-tert-Butyl4-formyl-2,2-dimethyloxazolidine-3-carboxylate 97%
5g
$ 236.00

Crysdot
(R)-tert-Butyl4-formyl-2,2-dimethyloxazolidine-3-carboxylate 97%
10g
$ 412.00

Chemenu
(R)-tert-Butyl4-formyl-2,2-dimethyloxazolidine-3-carboxylate 97%
100g
$ 2450.00

Biosynth Carbosynth
(4R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine
2 g
$ 168.00

Biosynth Carbosynth
(4R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine
1 g
$ 105.00

Total 91 raw suppliers

Chemical Property of (R)-tert-butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate Edit

Chemical Property:

Appearance/Colour:Clear pale yellow oil
Vapor Pressure:0.000972mmHg at 25°C
Refractive Index:1.445-1.447
Boiling Point:302.738 °C at 760 mmHg
PKA:-3.26±0.60(Predicted)
Flash Point:136.891 °C
PSA：55.84000
Density:1.129 g/cm³
LogP:1.49520
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Sensitive.:Air Sensitive
Solubility.:Chloroform, Dichloromethane, Ethyl Acetate
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:229.13140809
Heavy Atom Count:16
Complexity:293

Purity/Quality:

98%,99%, ^*data from raw suppliers

(4R)-3-tert-Butoxycarbonyl-2,2-dimethyl-4-formyloxazolidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 37/39-26-36-60-37-23

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1(N(C(CO1)C=O)C(=O)OC(C)(C)C)C
Isomeric SMILES:CC1(N([C@H](CO1)C=O)C(=O)OC(C)(C)C)C
Uses (R)-(+)-3-Boc-2,2-dimethyloxazolidine-4-carboxaldehyde is used in the preparation of fluorinated analogs of glutemic and glutamine.

Technology Process of (R)-tert-butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate

There total 38 articles about (R)-tert-butyl 4-formyl-2,2-dimethyloxazolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 108149-63-9,108149-65-1
tert-butyl (4S)-4-(hydroxymethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

: 95715-87-0
(R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine

Guidance literature:: tert-butyl (4S)-4-(hydroxymethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate; With oxalyl dichloride; In dichloromethane; dimethyl sulfoxide; at -60 - -45 ℃; for 0.666667h; Inert atmosphere;

With triethylamine; In dichloromethane; dimethyl sulfoxide; at -45 ℃; Inert atmosphere;
DOI:10.1039/c4md00136b