VEGF Receptor 2 Kinase Inhibitor I

Base Information

Chemical Name:VEGF Receptor 2 Kinase Inhibitor I
CAS No.:15966-93-5
Molecular Formula:C18H18N2O3
Molecular Weight:310.34700
Hs Code.:
UNII:U07H877HUF
Wikidata:Q27089130
Pharos Ligand ID:QNX3NM8BYV4A
ChEMBL ID:CHEMBL86943
Mol file:15966-93-5.mol

Synonyms:15966-93-5;VEGF Receptor 2 Kinase Inhibitor I;VEGFR2 Kinase Inhibitor I;SU5408;Vegfr 2 kinase inhibitor I;Vegfr-2 inhi;CHEMBL86943;U07H877HUF;ethyl 2,4-dimethyl-5-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrole-3-carboxylate;SU 5408;VEGFR2 kinase inhibitor I(SU-5408);1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester;3-(2,4-dimethyl-3-ethoxycarbonylpyrrol-5-methylidenyl)-2-indolinone;Ethyl 2,4-dimethyl-5-(((3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene)methyl)-1H-pyrrole-3-carboxylate;ethyl 2,4-dimethyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrole-3-carboxylate;D07OSK;K00004;UNII-U07H877HUF;SCHEMBL378979;GTPL6053;HMS3229O05;BDBM50065308;HSCI1_000034;AKOS037515527;CCG-206803;CS-7523;HY-103002;S6514;C73016;J-009628;Q27089130;(Z )-3-[(2,4-dimethyl-3-(ethoxycarbonyl)pyrrol-5-yl)methylidenyl]indolin-2-one;(Z)-ethyl 2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrole-3-carboxylate;{(Z)-3-[(2,4-Dimethyl-3-(ethoxycarbonyl)pyrrol-5-yl)methylidenyl]indolin-2-one;ethyl (Z)-2,4-dimethyl-5-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrole-3-carboxylate;(Z)-3-[(2,4-Dimethyl-3-(ethoxycarbonyl)pyrrol-5-yl)methylidenyl]indolin-2-one;2,4-Dimethyl-5-[2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-1H-pyrrole-3-carboxylic acid ethyl ester;210303-54-1

Suppliers and Price of VEGF Receptor 2 Kinase Inhibitor I

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
VEGFR 2 Kinase Inhibitor I
500μg
$ 319.00

TRC
VEGFR2KinaseInhibitorI
5mg
$ 395.00

DC Chemicals
VEGFR2kinaseinhibitorI(SU-5408) >98%
250 mg
$ 950.00

DC Chemicals
VEGFR2kinaseinhibitorI(SU-5408) >98%
1 g
$ 1800.00

DC Chemicals
VEGFR2kinaseinhibitorI(SU-5408) >98%
100 mg
$ 550.00

CSNpharm
SU5408
10mg
$ 806.00

CSNpharm
SU5408
25mg
$ 1798.00

CSNpharm
SU5408
5mg
$ 425.00

ChemScene
SU5408 ≥98.0%
25mg
$ 1980.00

ChemScene
SU5408 ≥98.0%
5mg
$ 468.00

Total 16 raw suppliers

Chemical Property of VEGF Receptor 2 Kinase Inhibitor I

Chemical Property:

Boiling Point:571.4±50.0 °C(Predicted)
PKA:12.40±0.20(Predicted)
PSA：71.19000
Density:1.271±0.06 g/cm3(Predicted)
LogP:3.43890
Storage Temp.:Sealed in dry,Store in freezer, under -20°C
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:310.13174244
Heavy Atom Count:23
Complexity:516

Purity/Quality:

99%, ^*data from raw suppliers

VEGFR 2 Kinase Inhibitor I ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(NC(=C1C)C=C2C3=CC=CC=C3NC2=O)C
Isomeric SMILES:CCOC(=O)C1=C(NC(=C1C)/C=C\2/C3=CC=CC=C3NC2=O)C
Uses VEGFR 2 Kinase Inhibitor blocks mutant huntingtin (Htt) cellular toxicity in Huntington’s disease.

Technology Process of VEGF Receptor 2 Kinase Inhibitor I

There total 1 articles about VEGF Receptor 2 Kinase Inhibitor I which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: