N-(5-chloro-4-methoxy-2-nitrophenyl)acetamide

Base Information

Chemical Name:N-(5-chloro-4-methoxy-2-nitrophenyl)acetamide
CAS No.:160088-53-9
Molecular Formula:C9H9ClN2O4
Molecular Weight:244.634
Hs Code.:2924299090
European Community (EC) Number:660-757-3
DSSTox Substance ID:DTXSID80381682
Wikidata:Q82172665
Mol file:160088-53-9.mol

Synonyms:N-(5-chloro-4-methoxy-2-nitrophenyl)acetamide;160088-53-9;Acetamide, N-(5-chloro-4-methoxy-2-nitrophenyl)-;5'-Chloro-4'-methoxy-2'-nitroacetanilide;N-(5-chloro-4-methoxy-2-nitrophenyl)-acetamide;SCHEMBL1291798;DTXSID80381682;MFCD00126497;AKOS015848444;KE-0840;CS-0061066;FT-0682634;W17980;n1-(5-chloro-4-methoxy-2-nitrophenyl)acetamide;A883244;J-523115

Suppliers and Price of N-(5-chloro-4-methoxy-2-nitrophenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
N-(5-Chloro-4-methoxy-2-nitrophenyl)acetamide
5g
$ 870.80

Alichem
N-(5-Chloro-4-methoxy-2-nitrophenyl)acetamide
5g
$ 651.45

American Custom Chemicals Corporation
N1-(5-CHLORO-4-METHOXY-2-NITROPHENYL)ACETAMIDE 95.00%
1G
$ 722.80

Crysdot
N-(5-Chloro-4-methoxy-2-nitrophenyl)acetamide 95+%
5g
$ 639.00

Matrix Scientific
N-(5-Chloro-4-methoxy-2-nitrophenyl)acetamide >95%
500mg
$ 181.00

Matrix Scientific
N-(5-Chloro-4-methoxy-2-nitrophenyl)acetamide >95%
1g
$ 228.00

Sigma-Aldrich
5'-CHLORO-4'-METHOXY-2'-NITROACETANILIDE AldrichCPR
1ea
$ 144.00

Total 9 raw suppliers

Chemical Property of N-(5-chloro-4-methoxy-2-nitrophenyl)acetamide

Chemical Property:

Boiling Point:447.2±45.0 °C(Predicted)
PKA:12.57±0.70(Predicted)
PSA：84.15000
Density:1.436±0.06 g/cm3(Predicted)
LogP:2.81140
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:244.0250845
Heavy Atom Count:16
Complexity:281

Purity/Quality:

97% ^*data from raw suppliers

N-(5-Chloro-4-methoxy-2-nitrophenyl)acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NC1=CC(=C(C=C1[N+](=O)[O-])OC)Cl

Technology Process of N-(5-chloro-4-methoxy-2-nitrophenyl)acetamide

There total 3 articles about N-(5-chloro-4-methoxy-2-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 7073-42-9
N-(3-chloro-4-methoxyphenyl)acetamide

: 160088-53-9
N-(5-chloro-4-methoxy-2-nitrophenyl)-acetamide

Guidance literature:: With sulfuric acid; nitric acid; at 0 ℃;

Reference yield:

: 5345-54-0
3-chloro-4-methoxyaniline

: 160088-53-9
N-(5-chloro-4-methoxy-2-nitrophenyl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 0.25 h / Heating

2: 60percent nitric acid, conc. sulfuric acid / 1.) 0 deg C, 10 min, 2.) RT, 30 min

With sulfuric acid; nitric acid; In acetic acid;
DOI:10.1021/jm00010a023

Reference yield:

: 4920-79-0
2-chloro-4-nitroanisole

: 160088-53-9
N-(5-chloro-4-methoxy-2-nitrophenyl)-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / iron, acetic acid / H₂O / 3 h / Heating

2: 80 percent / acetic acid / 0.25 h / 100 °C

3: 73 percent / conc. nitric acid, conc. H₂SO₄ / 0 °C

With sulfuric acid; nitric acid; iron; acetic acid; In water; acetic acid;