Benzene, 1-chloro-4-(propylthio)-

Base Information

• Chemical Name: Benzene, 1-chloro-4-(propylthio)-
• CAS No.: 16155-32-1
• Molecular Formula: C9H11ClS
• Molecular Weight: 186.705
• Mol file: 16155-32-1.mol

Synonyms:1-chloro-4-propylthiobenzene;p-chlorophenyl propyl sulfide;Propyl-(4-chlorphenyl)-sulfid;

Chemical Property of Benzene, 1-chloro-4-(propylthio)-

Chemical Property:

• PSA: 25.30000
• LogP: 3.84210

Purity/Quality:

99% ^*data from raw suppliers

p-Chlorophenylpropylsulfide 99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 1-chloro-4-(propylthio)-

There total 6 articles about Benzene, 1-chloro-4-(propylthio)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

propyl bromide (106-94-5) + p-Chlorothiophenol (106-54-7) → p-chlorphenyl n-propyl sulfide (16155-32-1)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; for 12h;

DOI:10.1021/ja068808s

Reference yield: 99.0%

4,4'-dichlorodiphenyl disulfide (1142-19-4) + propyl benzoate (2315-68-6) → p-chlorphenyl n-propyl sulfide (16155-32-1)

Guidance literature:

With hexamethyldisilathiane; potassium carbonate; In 1-methyl-pyrrolidin-2-one; at 120 ℃; for 8h; Sealed tube;

DOI:10.1002/asia.202101101

Reference yield: 93.0%

4,4'-dichlorodiphenyl disulfide (1142-19-4) + propyl bromide (106-94-5) → p-chlorphenyl n-propyl sulfide (16155-32-1)

Guidance literature:

With water; rongalite; potassium carbonate; In N,N-dimethyl-formamide; for 0.25h;

DOI:10.1055/s-2006-950363

upstream raw materials:

1-chloro-4-[(3-chloropropyl)thio]benzene

propyl bromide

p-Chlorothiophenol

4,4'-dichlorodiphenyl disulfide

Downstream raw materials:

1,1,2-trifluoro-2-(p-chlorophenylthio)propane

(S_S)-p-chlorophenyl propyl sulfoxide

1-[1-(4-Chloro-phenylsulfanyl)-propoxy]-2,4-diethyl-benzene

C₁₆H₁₇ClOS

Refernces

• 1、 Blakemore, Paul R.,Burge, Matthew S.. "Iterative stereospecific reagent-controlled homologation of pinacol boronates by enantioenriched α-chloroalkyllithium reagents". . p. 3068 - 3069. Retrieved 2008/02/05.
• 2、 Tang, Ri-Yuan,Zhong, Ping,Lin, Qiu-Lian. "One-pot synthesis of sulfides by reaction of disulfides with alkyl halides in the presence of sodium dithionite". . p. 167 - 174. Retrieved 2007/10/03.