Technology Process of methyl 7-methoxy-1-(2-methoxy-2-oxoethyl)-2-methyl-3,4-dihydro-1H-phenanthrene-2-carboxylate
There total 26 articles about methyl 7-methoxy-1-(2-methoxy-2-oxoethyl)-2-methyl-3,4-dihydro-1H-phenanthrene-2-carboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
palladium on activated charcoal;
at 300 ℃;
DOI:10.1007/BF03251062
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 57 percent / POCl3 / CH2Cl2 / 8 h / Ambient temperature
2: 78 percent / triethylamine / benzene / 30 h / Heating
3: 78.7 percent / 2,3-dichloro-5,6-dicyanobenzoquinone, acetic acid / benzene / 1.) 1 h, ice-bath, 2.) 3 h, room temperature
4: Zn
5: 1.) trimethylchlorosilane, sodium iodide, 2.) acetic acid, zinc / 1.) acetonitrile, 3 h, 2.) 2 h
With
chloro-trimethyl-silane; acetic acid; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium iodide; zinc; trichlorophosphate;
In
dichloromethane; benzene;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 57 percent / POCl3 / CH2Cl2 / 8 h / Ambient temperature
2: 78 percent / triethylamine / benzene / 30 h / Heating
3: 78.7 percent / 2,3-dichloro-5,6-dicyanobenzoquinone, acetic acid / benzene / 1.) 1 h, ice-bath, 2.) 3 h, room temperature
4: Zn
5: 1.) triethylsilane, trifluoroacetic acid, 2.) sodium hydroxide / 1.) dichloromethane, 15 min, ice-salt bath, 30 min, room temperature, 2.) methanol, overnight
6: 88 mg / ethyl acetate
With
triethylsilane; sodium hydroxide; acetic acid; triethylamine; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; zinc; trichlorophosphate;
In
dichloromethane; ethyl acetate; benzene;
