2-Chloro-5-methanesulfonylaniline

Base Information

• Chemical Name: 2-Chloro-5-methanesulfonylaniline
• CAS No.: 16328-56-6
• Molecular Formula: C7H8ClNO2S
• Molecular Weight: 205.66200
• European Community (EC) Number: 834-049-1
• Mol file: 16328-56-6.mol

Synonyms:2-chloro-5-methanesulfonylaniline;16328-56-6;2-chloro-5-methylsulfonylaniline;2-chloro-5-(methylsulfonyl)aniline;Benzenamine, 2-chloro-5-(methylsulfonyl)-;SCHEMBL1370002;HMS1725E17;2-chloro-5-methanesulfonyl-aniline;MFCD00087724;AKOS002662894;BS-13657;CS-0247006;EN300-35246;SR-01000036226;SR-01000036226-1;Z56858239

Chemical Property of 2-Chloro-5-methanesulfonylaniline

Chemical Property:

• PSA: 68.54000
• LogP: 2.98770
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 204.9964274
• Heavy Atom Count: 12
• Complexity: 247

Purity/Quality:

95% ^*data from raw suppliers

2-chloro-5-methanesulfonylaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)C1=CC(=C(C=C1)Cl)N

Technology Process of 2-Chloro-5-methanesulfonylaniline

There total 1 articles about 2-Chloro-5-methanesulfonylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 1-amino-2-chloro-5-methylsulfonylbenzene (16328-56-6)

Guidance literature:

Reference yield:

1-amino-2-chloro-5-methylsulfonylbenzene (16328-56-6) → C14H12N2O4S3 (1429321-56-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite; hydrogenchloride; sulfur dioxide; acetic acid; copper dichloride

2: potassium carbonate / acetone / Reflux

With hydrogenchloride; sulfur dioxide; potassium carbonate; acetic acid; copper dichloride; sodium nitrite; In acetone;

DOI:10.1021/jm301743b

Reference yield:

1-amino-2-chloro-5-methylsulfonylbenzene (16328-56-6) → C16H16N2O4S3 (1429321-57-2)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite; hydrogenchloride; sulfur dioxide; acetic acid; copper dichloride

2: potassium carbonate / acetone / Reflux

With hydrogenchloride; sulfur dioxide; potassium carbonate; acetic acid; copper dichloride; sodium nitrite; In acetone;

DOI:10.1021/jm301743b

Downstream raw materials:

C₁₄H₁₂N₂O₄S₃

C₁₆H₁₆N₂O₄S₃

2-chloro-5-(methylsulfonyl)benzenesulfonamide