(2,3-dichlorophenyl)methanesulfonyl Chloride

Base Information

• Chemical Name: (2,3-dichlorophenyl)methanesulfonyl Chloride
• CAS No.: 163295-69-0
• Molecular Formula: C7H5Cl3O2S
• Molecular Weight: 259.541
• Hs Code.: 2904990090
• DSSTox Substance ID: DTXSID60466981
• Wikidata: Q82293698
• Mol file: 163295-69-0.mol

Synonyms:(2,3-dichlorophenyl)methanesulfonyl Chloride;163295-69-0;(2,3-Dichlorophenyl)methanesulphonyl chloride;MFCD11976102;SCHEMBL271468;DTXSID60466981;UGTSPJDUUYLVMM-UHFFFAOYSA-N;AKOS011364622;PS-10886;(2,3-Dichlorophenyl)methanesulphonylchloride;(2,3-dichlorophenyl)-methanesulfonyl chloride;Benzenemethanesulfonyl chloride, 2,3-dichloro-;EN300-104229

Chemical Property of (2,3-dichlorophenyl)methanesulfonyl Chloride

Chemical Property:

• Boiling Point: 353.1±32.0 °C(Predicted)
• PSA: 42.52000
• Density: 1.601±0.06 g/cm3(Predicted)
• LogP: 4.14280
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 257.907584
• Heavy Atom Count: 13
• Complexity: 259

Purity/Quality:

99% ^*data from raw suppliers

(2,3-Dichlorophenyl)methanesulfonyl chloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)Cl)Cl)CS(=O)(=O)Cl

Technology Process of (2,3-dichlorophenyl)methanesulfonyl Chloride

There total 2 articles about (2,3-dichlorophenyl)methanesulfonyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2,3-dichlorophenyl)-methanesulfonic acid → (2,3-dichlorophenyl)methanesulfonyl chloride (163295-69-0)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; at 0 - 20 ℃; for 1.5h;

Reference yield:

→ (2,3-dichlorophenyl)methanesulfonyl chloride (163295-69-0)

Guidance literature:

Reference yield: 50.0%

(2,3-dichlorophenyl)methanesulfonyl chloride (163295-69-0) + methyl 4-{2-[2-(2-aminoethyl)-1-benzhydryl-5-chloro-1H-indol-3-yl]ethoxy}benzoate amine (540522-69-8) → methyl 4-{2-[5-chloro-2-(2-{[(2,3-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]ethoxy}benzoate (683813-12-9)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane;

DOI:10.1021/jm061131z

Downstream raw materials:

methyl 4-{2-[5-chloro-2-(2-{[(2,3-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]ethoxy}benzoate