ethyl 3,5-dimethyl-1H-indole-2-carboxylate

Base Information

Chemical Name:ethyl 3,5-dimethyl-1H-indole-2-carboxylate
CAS No.:16423-76-0
Molecular Formula:C₁₃H₁₅NO₂
Molecular Weight:217.268
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50408451
Nikkaji Number:J1.357.132E
Wikidata:Q82213933
Mol file:16423-76-0.mol

Synonyms:ethyl 3,5-dimethyl-1H-indole-2-carboxylate;16423-76-0;1H-Indole-2-carboxylic acid, 3,5-dimethyl-, ethyl ester;SCHEMBL7688090;DTXSID50408451;SOBSEOUZZDHRIZ-UHFFFAOYSA-N;MFCD00454154;AKOS004119614;Ethyl 3,5-dimethyl-2-indolecarboxylate;LS-03446;ethyl3,5-dimethyl-1H-indole-2-carboxylate;CS-0324231

Suppliers and Price of ethyl 3,5-dimethyl-1H-indole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 3,5-dimethyl-1H-indole-2-carboxylate
500mg
$ 289.00

Matrix Scientific
Ethyl 3,5-dimethyl-1H-indole-2-carboxylate
1g
$ 323.00

Crysdot
Ethyl3,5-dimethyl-1H-indole-2-carboxylate 97%
5g
$ 904.00

Chemenu
Ethyl3,5-dimethyl-1H-indole-2-carboxylate 95%+
1g
$ 302.00

Chemenu
Ethyl3,5-dimethyl-1H-indole-2-carboxylate 95%+
5g
$ 853.00

American Custom Chemicals Corporation
1H-INDOLE-2-CARBOXYLIC ACID, 3,5-DIMETHYL-, ETHYL ESTER 95.00%
5MG
$ 495.26

AK Scientific
Ethyl3,5-dimethyl-1H-indole-2-carboxylate
1g
$ 486.00

Total 4 raw suppliers

Chemical Property of ethyl 3,5-dimethyl-1H-indole-2-carboxylate

Chemical Property:

Melting Point:131-133 °C
Boiling Point:357.1±37.0 °C(Predicted)
PKA:15.49±0.30(Predicted)
PSA：42.09000
Density:1.150±0.06 g/cm3(Predicted)
LogP:2.96140
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:217.110278721
Heavy Atom Count:16
Complexity:267

Purity/Quality:

99% ^*data from raw suppliers

Ethyl 3,5-dimethyl-1H-indole-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C2=C(N1)C=CC(=C2)C)C

Technology Process of ethyl 3,5-dimethyl-1H-indole-2-carboxylate

There total 9 articles about ethyl 3,5-dimethyl-1H-indole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 106-49-0,12221-03-3
p-toluidine

: 607-97-6
ethyl 2-ethyl-3-oxobutanoate

: 16423-76-0
ethyl 3,5-dimethyl-1H-indole-2-carboxylate

Guidance literature:: p-toluidine; With hydrogenchloride; sodium acetate; sodium nitrite; In water; at -5 - 0 ℃; for 0.25h; pH=3.4;

ethyl 2-ethyl-3-oxobutanoate; With potassium hydroxide; In ethanol; water; at 0 ℃; for 15h; pH=5 - 6;

With hydrogenchloride; In ethanol; for 2h; Heating / reflux;