2S-hydroxyhexadecanoic acid

Base Information

Chemical Name:2S-hydroxyhexadecanoic acid
CAS No.:16452-52-1
Molecular Formula:C16H32O3
Molecular Weight:272.428
Hs Code.:
Metabolomics Workbench ID:72082
Nikkaji Number:J660.092A
Wikidata:Q27145669
Mol file:16452-52-1.mol

Synonyms:2S-hydroxyhexadecanoic acid;2S-hydroxypalmitic acid;(S)-2OH PA;(S)-2-hydroxypalmitic acid;(2S)-2-hydroxyhexadecanoic acid;(S)-2-hydroxyhexadecanoic acid;(11s)-hydroxyhexadecanoic acid;SCHEMBL6237434;CHEBI:75977;JGHSBPIZNUXPLA-HNNXBMFYSA-N;LMFA01050422;(S)-(-)-2-hydroxyhexadecanoic acid;Q27145669

Suppliers and Price of 2S-hydroxyhexadecanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2S-hydroxyhexadecanoic acid

Chemical Property:

XLogP3:6.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:14
Exact Mass:272.23514488
Heavy Atom Count:19
Complexity:204

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCCCCCCCCCCCC(C(=O)O)O
Isomeric SMILES:CCCCCCCCCCCCCC[C@@H](C(=O)O)O

Technology Process of 2S-hydroxyhexadecanoic acid

There total 15 articles about 2S-hydroxyhexadecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.3%

: 78330-57-1
(2S)-2-hydroxyhexadecanoic acid methyl ester

: 16452-52-1,10067-06-8
(S)-2-hydroxyhexadecanoic acid

Guidance literature:: With potassium hydroxide; In ethanol; at 70 ℃; for 0.333333h;

Reference yield:

: 7769-79-1
2-aminohexadecanoic acid

: 16452-52-1,10067-06-8
(S)-2-hydroxyhexadecanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 86.1 percent / 2N NaOH aq., (EtOCH₂CH₂)2O, cc. HCl / 1 h / 10 °C

2: 99.5 percent / 4N HCl / 3 h / Heating

3: aq. NaNO₂, 2N H₂SO₄, / 2 h / 80 °C / r.t., 18 h

4: cc. HCl / methanol; benzene / 3.5 h / Heating

5: KOH / aq. ethanol / 0.5 h / Heating

With hydrogenchloride; potassium hydroxide; sodium hydroxide; 3,6,9-trioxaundecane; sulfuric acid; sodium nitrite; In methanol; ethanol; benzene;
DOI:10.1016/S0040-4020(01)96632-3