1-Chloro-4-(2-phenylcyclopropyl)sulfonylbenzene

Base Information

• Chemical Name: 1-Chloro-4-(2-phenylcyclopropyl)sulfonylbenzene
• CAS No.: 21309-07-9
• Molecular Formula: C₁₅H₁₃ClO₂S
• Molecular Weight: 292.786
• NSC Number: 140185
• DSSTox Substance ID: DTXSID30943815
• Mol file: 21309-07-9.mol

Synonyms:21309-07-9;NSC140185;DTXSID30943815;NSC-140185;1-Chloro-4-(2-phenylcyclopropane-1-sulfonyl)benzene

Chemical Property of 1-Chloro-4-(2-phenylcyclopropyl)sulfonylbenzene

Chemical Property:

• Vapor Pressure: 1.34E-08mmHg at 25°C
• Boiling Point: 471.3°C at 760 mmHg
• Flash Point: 238.8°C
• Density: 1.351g/cm³
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 292.0324785
• Heavy Atom Count: 19
• Complexity: 400

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(C1S(=O)(=O)C2=CC=C(C=C2)Cl)C3=CC=CC=C3

Technology Process of 1-Chloro-4-(2-phenylcyclopropyl)sulfonylbenzene

There total 5 articles about 1-Chloro-4-(2-phenylcyclopropyl)sulfonylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.6%

1-Chloro-4-((1R,2R)-2-phenyl-cyclopropylsulfanyl)-benzene → cis-1-(4-chlorobenzenesulphonyl)-2-phenylcyclopropane (21309-07-9,72856-82-7,73628-16-7)

Guidance literature:

With dihydrogen peroxide; In acetic acid; Heating;

Reference yield:

p-Chlorothiophenol (106-54-7) → cis-1-(4-chlorobenzenesulphonyl)-2-phenylcyclopropane (21309-07-9,72856-82-7,73628-16-7)

Guidance literature:

Multi-step reaction with 3 steps

1: concd. HCl / benzene / 2 h / 40 °C

2: 59 percent / t-BuOK / 3 h

3: 78.6 percent / 30percent H₂O₂ / acetic acid / Heating

With hydrogenchloride; potassium tert-butylate; dihydrogen peroxide; In acetic acid; benzene;

Reference yield:

chloromethyl 4-chlorophenyl sulfide (7205-90-5) → cis-1-(4-chlorobenzenesulphonyl)-2-phenylcyclopropane (21309-07-9,72856-82-7,73628-16-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 59 percent / t-BuOK / 3 h

2: 78.6 percent / 30percent H₂O₂ / acetic acid / Heating

With potassium tert-butylate; dihydrogen peroxide; In acetic acid;

upstream raw materials:

styrene

chloromethyl 4-chlorophenyl sulfide

4-chlorobenzenesulfonyl chloride

p-Chlorothiophenol

Refernces