4-Hydroxyquinoline-2-carbaldehyde

Base Information

Chemical Name:4-Hydroxyquinoline-2-carbaldehyde
CAS No.:168141-99-9
Molecular Formula:C10H7NO2
Molecular Weight:173.16800
Hs Code.:2933499090
European Community (EC) Number:685-754-4
DSSTox Substance ID:DTXSID20405674
Wikidata:Q82210350
Mol file:168141-99-9.mol

Synonyms:4-Hydroxyquinoline-2-carbaldehyde;168141-99-9;4-oxo-1H-quinoline-2-carbaldehyde;2-Quinolinecarboxaldehyde, 4-hydroxy-;CHEMBRDG-BB 4014212;SCHEMBL9071311;DTXSID20405674;4-Hydroxy-2-quinolinecarbaldehyde;MFCD06408352;AKOS002669599;FS-6224;SB68098;CS-0245378;4-hydroxyquinoline-2-carbaldehyde, AldrichCPR;EN300-304076;Z1198168675

Suppliers and Price of 4-Hydroxyquinoline-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-hydroxyquinoline-2-carbaldehyde
100mg
$ 110.00

ChemBridge Corporation
4-hydroxyquinoline-2-carbaldehyde 95%
200 μmol
$ 95.00

American Custom Chemicals Corporation
4-HYDROXYQUINOLINE-2-CARBALDEHYDE 95.00%
10G
$ 2279.97

American Custom Chemicals Corporation
4-HYDROXYQUINOLINE-2-CARBALDEHYDE 95.00%
5G
$ 1491.68

American Custom Chemicals Corporation
4-HYDROXYQUINOLINE-2-CARBALDEHYDE 95.00%
1G
$ 818.61

Alichem
4-Hydroxyquinoline-2-carboxaldehyde
1g
$ 296.43

AccelPharmtech
4-hydroxy-2-Quinolinecarboxaldehyde 97.00%
25G
$ 13300.00

AccelPharmtech
4-hydroxy-2-Quinolinecarboxaldehyde 97.00%
5G
$ 5360.00

Total 7 raw suppliers

Chemical Property of 4-Hydroxyquinoline-2-carbaldehyde

Chemical Property:

Vapor Pressure:0.00024mmHg at 25°C
Boiling Point:324.8oC at 760 mmHg
PKA:3.57±0.40(Predicted)
Flash Point:150oC
PSA：50.19000
Density:1.367g/cm3
LogP:1.75290
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:173.047678466
Heavy Atom Count:13
Complexity:270

Purity/Quality:

99% ^*data from raw suppliers

4-hydroxyquinoline-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)C=C(N2)C=O

Technology Process of 4-Hydroxyquinoline-2-carbaldehyde

There total 2 articles about 4-Hydroxyquinoline-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 168141-98-8
4-hydroxy-2-hydroxymethylquinoline

: 168141-99-9
4-hydroxyquinoline-2-carbaldehyde

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -60 ℃; for 0.25h;

Reference yield:

: 492-27-3
kinurenic acid

: 168141-99-9
4-hydroxyquinoline-2-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / 1 M THF*BH₃ / tetrahydrofuran / 3 h / Ambient temperature

2: 70 percent / DMSO, (COCl)2 / CH₂Cl₂ / 0.25 h / -60 °C

With borane-THF; oxalyl dichloride; dimethyl sulfoxide; In tetrahydrofuran; dichloromethane;