5,6-Dihydro-3-methyl-6-(4-nitrophenyl)-4H-pyrrolo(1,2-a)thieno(3,2-f)(1,4)diazepine

Base Information

Chemical Name:5,6-Dihydro-3-methyl-6-(4-nitrophenyl)-4H-pyrrolo(1,2-a)thieno(3,2-f)(1,4)diazepine
CAS No.:137052-96-1
Molecular Formula:C₁₇H₁₅N₃O₂S
Molecular Weight:325.391
Hs Code.:
DSSTox Substance ID:DTXSID30929694
Nikkaji Number:J618.398K

Synonyms:5,6-Dihydro-3-methyl-6-(4-nitrophenyl)-4H-pyrrolo(1,2-a)thieno(3,2-f)(1,4)diazepine;4H-Pyrrolo(1,2-a)thieno(3,2-f)(1,4)diazepine, 5,6-dihydro-3-methyl-6-(4-nitrophenyl)-;137052-96-1;DTXSID30929694;LS-139747;3-Methyl-5,6-dihydro-6-(4-nitrophenyl)-4H-pyrrolo[1,2-a]thieno[3,2-f][1,4]diazepine;3-Methyl-6-(4-nitrophenyl)-5,6-dihydro-4H-pyrrolo[1,2-a]thieno[3,2-f][1,4]diazepine

Suppliers and Price of 5,6-Dihydro-3-methyl-6-(4-nitrophenyl)-4H-pyrrolo(1,2-a)thieno(3,2-f)(1,4)diazepine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5,6-Dihydro-3-methyl-6-(4-nitrophenyl)-4H-pyrrolo(1,2-a)thieno(3,2-f)(1,4)diazepine

Chemical Property:

Vapor Pressure:2.31E-11mmHg at 25°C
Boiling Point:531.1°C at 760 mmHg
Flash Point:275°C
Density:1.43g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:325.08849790
Heavy Atom Count:23
Complexity:450

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CSC2=C1CNC(C3=CC=CN32)C4=CC=C(C=C4)[N+](=O)[O-]

Technology Process of 5,6-Dihydro-3-methyl-6-(4-nitrophenyl)-4H-pyrrolo(1,2-a)thieno(3,2-f)(1,4)diazepine

There total 6 articles about 5,6-Dihydro-3-methyl-6-(4-nitrophenyl)-4H-pyrrolo(1,2-a)thieno(3,2-f)(1,4)diazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 160916-17-6
1-<2-(3-p-nitro-benzylideneaminomethyl-4-methyl)thien-2-yl>pyrrole

: 137052-96-1
3-Methyl-6-(4-nitro-phenyl)-5,6-dihydro-4H-1-thia-5,9a-diaza-cyclopenta[e]azulene

Guidance literature:: With hydrogenchloride; sodium hydroxide; ethanol; water; for 0.75h; Ambient temperature;
DOI:10.1002/ardp.19943271108

Reference yield:

: 4623-55-6
2-amino-4-methylthiophene-3-carbonitrile

: 137052-96-1
3-Methyl-6-(4-nitro-phenyl)-5,6-dihydro-4H-1-thia-5,9a-diaza-cyclopenta[e]azulene

Guidance literature:: Multi-step reaction with 4 steps

1: 62 percent / glacial acetic acid / 0.5 h / Heating

2: 91 percent / LiAlH₄ / diethyl ether / 24 h / Heating

3: 90 percent / ethanol / 0.25 h / Heating

4: 73 percent / 1.) saturated HCl/EtOH, 2.) dil. NaOH/H₂O / 0.75 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; lithium aluminium tetrahydride; ethanol; water; acetic acid; In diethyl ether; ethanol;
DOI:10.1002/ardp.19943271108

Reference yield:

: 160916-15-4
1-<2-(3-aminomethyl-4-methyl)thien-2-yl>pyrrole

: 137052-96-1
3-Methyl-6-(4-nitro-phenyl)-5,6-dihydro-4H-1-thia-5,9a-diaza-cyclopenta[e]azulene

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / ethanol / 0.25 h / Heating

2: 73 percent / 1.) saturated HCl/EtOH, 2.) dil. NaOH/H₂O / 0.75 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; ethanol; water; In ethanol;
DOI:10.1002/ardp.19943271108