4-Fluoro-2-(trifluoromethyl)benzylamine

Base Information

Chemical Name:4-Fluoro-2-(trifluoromethyl)benzylamine
CAS No.:202522-22-3
Molecular Formula:C8H7F4N
Molecular Weight:193.144
Hs Code.:29214200
European Community (EC) Number:671-100-5
DSSTox Substance ID:DTXSID10370549
Wikidata:Q72477440
Mol file:202522-22-3.mol

Synonyms:202522-22-3;4-Fluoro-2-(trifluoromethyl)benzylamine;(4-Fluoro-2-(trifluoromethyl)phenyl)methanamine;[4-fluoro-2-(trifluoromethyl)phenyl]methanamine;4-Fluoro-2-(trifluoromethyl)benzyl amine;4-Fluoro-2-(trifluoromethyl)benzenemethanamine;Benzenemethanamine, 4-fluoro-2-(trifluoromethyl)-;1-[4-fluoro-2-(trifluoromethyl)phenyl]methanamine;4-Fluoro-2-trifluoromethylbenzylamine;Benzenemethanamine,4-fluoro-2-(trifluoromethyl)-;SCHEMBL109671;DTXSID10370549;2-trifluoromethyl-4-fluorobenzylamine;CK2393;MFCD00061164;4-fluoro-2-trifluoromethyl benzylamine;AKOS009157268;CS-W015787;PS-8322;FT-0618451;4-FLUORO-2-TRIFLUOROMETHYLBENZYL AMINE;EN300-40141;(4-fluoro-2-(trifluoromethyl)phenyl)-methanamine;{[4-fluoro-2-(trifluoromethyl)phenyl]methyl}amine;A814360;J-013151;Z407959090

Suppliers and Price of 4-Fluoro-2-(trifluoromethyl)benzylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Fluoro-2-(trifluoromethyl)benzenemethanamine
100mg
$ 130.00

SynQuest Laboratories
4-Fluoro-2-(trifluoromethyl)benzylamine 97%
25 g
$ 373.00

SynQuest Laboratories
4-Fluoro-2-(trifluoromethyl)benzylamine 97%
5 g
$ 114.00

Oakwood
4-Fluoro-2-(trifluoromethyl)benzylamine 99%
5g
$ 37.00

Oakwood
4-Fluoro-2-(trifluoromethyl)benzylamine 99%
1g
$ 20.00

Oakwood
4-Fluoro-2-(trifluoromethyl)benzylamine 99%
25g
$ 112.00

Matrix Scientific
4-Fluoro-2-(trifluoromethyl)benzylamine 97%
25g
$ 117.00

Matrix Scientific
4-Fluoro-2-(trifluoromethyl)benzylamine 97%
5g
$ 37.00

Frontier Specialty Chemicals
4-Fluoro-2-(trifluoromethyl)benzylamine
1g
$ 80.00

Frontier Specialty Chemicals
4-Fluoro-2-(trifluoromethyl)benzylamine
5g
$ 273.00

Total 34 raw suppliers

Chemical Property of 4-Fluoro-2-(trifluoromethyl)benzylamine

Chemical Property:

Vapor Pressure:1.04mmHg at 25°C
Refractive Index:1.453
Boiling Point:177.439 °C at 760 mmHg
PKA:8.21±0.10(Predicted)
Flash Point:72.7 °C
PSA：26.02000
Density:1.313 g/cm³
LogP:3.00350
Storage Temp.:Store under nitrogen
Sensitive.:Air Sensitive
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:193.05146188
Heavy Atom Count:13
Complexity:168

Purity/Quality:

97% ^*data from raw suppliers

4-Fluoro-2-(trifluoromethyl)benzenemethanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): C, Xi
Hazard Codes:C,Xi
Statements: 34
Safety Statements: 45-36/37/39-26-23-20

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)C(F)(F)F)CN
Uses 4-Fluoro-2-(trifluoromethyl)benzylamine is used for preparation of heterocycle-substituted amide derivatives as ACAT inhibitors for pharmaceuticals compositions.

Technology Process of 4-Fluoro-2-(trifluoromethyl)benzylamine

There total 1 articles about 4-Fluoro-2-(trifluoromethyl)benzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 194853-86-6
4-fluoro-2-(trifluoromethyl)benzonitrile

: 202522-22-3
(4-fluoro-2-(trifluoromethyl)phenyl)methanamine

Guidance literature:: With hydrogen; Raney Ni; In ethanol; under 2585.81 Torr;

Reference yield: 97.0%

: 202522-22-3
(4-fluoro-2-(trifluoromethyl)phenyl)methanamine

: (E)-N-[4-fluoro-2-(trifluoromethyl)benzyl]-1-[4-fluoro-2-(trifluoromethyl)phenyl]-methanimine

Guidance literature:: With S₈ stabilised CuO and Cu₂O nanoparticle; air; In neat (no solvent); at 20 ℃; for 24h;
DOI:10.1039/d0ta12621g

Reference yield: 91.0%

: 50593-73-2
4-chloro-6-methoxy-2-methylquinoline

: 202522-22-3
(4-fluoro-2-(trifluoromethyl)phenyl)methanamine

: N-[4-fluoro-2-(trifluoromethyl)benzyl]-6-methoxy-2-methylquinolin-4-amine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In 1,4-dioxane; at 110 ℃; Inert atmosphere;
DOI:10.1021/acs.jmedchem.1c01609