4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide

Base Information

Chemical Name:4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
CAS No.:170570-09-9
Molecular Formula:C₁₈H₁₆F₃N₃O₂S
Molecular Weight:395.405
Hs Code.:2933194350
UNII:FU7XND9V2J
Nikkaji Number:J1.692.278A
Pharos Ligand ID:KZV8WLFG7MYQ
ChEMBL ID:CHEMBL283038
Mol file:170570-09-9.mol

Synonyms:2-Methyl-Celecoxib;170570-09-9;2-Methyl celecoxib;FU7XND9V2J;4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide;CHEMBL283038;4-(5-(2,4-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide;4-[5-(2,4-dimethylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide;Benzenesulfonamide, 4-(5-(2,4-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)-;2,4-Dimethyl Celecoxib;UNII-FU7XND9V2J;SCHEMBL6352145;CDMHSMOZNZFYIK-UHFFFAOYSA-N;EX-A3207;VGA57009;BDBM50057525;B0070-468627;4-[3-(Trifluoromethyl)-5-(2,4-dimethylphenyl)-1H-pyrazole-1-yl]benzenesulfonamide;4-(5-(2,4-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide;p-[3-(Trifluoromethyl)-5-(2,4-xylyl)-1H-pyrazol-1-yl]benzenesulfonamide

Suppliers and Price of 4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methyl-Celecoxib
1g
$ 1360.00

Total 12 raw suppliers

Chemical Property of 4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide

Chemical Property:

Boiling Point:521.9±60.0 °C(Predicted)
PKA:9.68±0.10(Predicted)
PSA：86.36000
Density:1.40±0.1 g/cm3(Predicted)
LogP:5.60340
XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:395.09153242
Heavy Atom Count:27
Complexity:614

Purity/Quality:

NLT 98% ^*data from raw suppliers

2-Methyl-Celecoxib ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)C
Uses 2-Methyl-Celecoxib is an analog of the anti-inflammatory drug Celecoxib (C251000). Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor.

Technology Process of 4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide

There total 1 articles about 4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: