1-METHYL-5-TRIBUTYLSTANNANYL-1H-[1,2,3]TRIAZOLE

Base Information

• Chemical Name: 1-METHYL-5-TRIBUTYLSTANNANYL-1H-[1,2,3]TRIAZOLE
• CAS No.: 170681-98-8
• Molecular Formula: C15H31N3Sn
• Molecular Weight: 372.141
• Mol file: 170681-98-8.mol

Synonyms:1-methyl-5-(tributylstannyl)-1,2,3-triazole;1-methyl-5-(tributylstannyl)-1H-1,2,3-triazole;1-METHYL-5-TRIBUTYLSTANNANYL-1H-[1,2,3]TRIAZOLE;1-methyl-5-tributylstannanyl-[1,2,3]triazole;1H-1,2,3-Triazole,1-methyl-5-(tributylstannyl);

Chemical Property of 1-METHYL-5-TRIBUTYLSTANNANYL-1H-[1,2,3]TRIAZOLE

Chemical Property:

• Boiling Point: 391.8±52.0 °C(Predicted)
• PKA: 1.38±0.10(Predicted)
• PSA: 30.71000
• LogP: 3.56090

Purity/Quality:

98%min ^*data from raw suppliers

1-Methyl-5-tributylstannanyl-1H-[1,2,3]triazole >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-METHYL-5-TRIBUTYLSTANNANYL-1H-[1,2,3]TRIAZOLE

There total 1 articles about 1-METHYL-5-TRIBUTYLSTANNANYL-1H-[1,2,3]TRIAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1-methyl-1,2,3-triazole (16681-65-5) + tributyltin chloride (1461-22-9) → 1-methyl-5-tributylstannanyl-1H-[1,2,3]triazole (170681-98-8)

Guidance literature:

1-methyl-1,2,3-triazole; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 2h;

tributyltin chloride; In tetrahydrofuran; at -78 - 20 ℃; for 2h;

Reference yield: 45.0%

1-methyl-5-tributylstannanyl-1H-[1,2,3]triazole (170681-98-8) + (4-benzyloxy-phenyl)-(6-bromoquinazolin-4-yl)-amine (179248-66-9) → (4-Benzyloxy-phenyl)-(6-(3-methyl-1,2,3-triazol-4-yl)-quinazolin-4-yl)-amine (202196-45-0)

Guidance literature:

bis(triphenylphosphine)palladium(II)-chloride; In 1,4-dioxane; ethyl acetate;

Reference yield: 44.0%

1-methyl-5-tributylstannanyl-1H-[1,2,3]triazole (170681-98-8) + N2-(4-bromo-2-chloro-5-methoxyphenyl)-N4-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine (1440964-36-2) → N2-(2-chloro-5-methoxy-4-(1-methyl-1H-1,2,3-triazol-5-yl)phenyl)-N4-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine (1440963-66-5)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 100 ℃; for 90h;

upstream raw materials:

1-methyl-1,2,3-triazole

tributyltin chloride

Downstream raw materials:

(4-Benzyloxy-phenyl)-(6-(3-methyl-1,2,3-triazol-4-yl)-quinazolin-4-yl)-amine

methyl 4-(1-methyl-1H-1,2,3-triazol-5-yl)benzoate

N₂-(2-chloro-5-methoxy-4-(1-methyl-1H-1,2,3-triazol-5-yl)phenyl)-N₄-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine