4,5-Dimethoxyphthalic acid dimethyl ester

Base Information

• Chemical Name: 4,5-Dimethoxyphthalic acid dimethyl ester
• CAS No.: 17078-61-4
• Molecular Formula: C12H14O6
• Molecular Weight: 254.24
• Hs Code.: 2918990090
• Mol file: 17078-61-4.mol

Synonyms:1,2-Benzenedicarboxylic acid,4,5-dimethoxy-,dimethyl ester;Metahemipinsaeure-dimethylester;x-<14C>-Metahemipinsaeure-dimethylester;dimethyl 3,4-dimethoxy-1,6-benzenedicarboxylate;Dimethyl 4,5-dimethoxyphthalate;4,5-dimethoxy-phthalic acid dimethyl ester;dimethyl meta-hemipinate;4,5-Dimethoxy-phthalsaeure-dimethylester;

Chemical Property of 4,5-Dimethoxyphthalic acid dimethyl ester

Chemical Property:

• PSA: 71.06000
• LogP: 1.27700
• Storage Temp.: 2-8°C

Purity/Quality:

≥99% ^*data from raw suppliers

Dimethyl4,5-dimethoxyphthalate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,5-Dimethoxyphthalic acid dimethyl ester

There total 10 articles about 4,5-Dimethoxyphthalic acid dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,5-Dimethoxy-cyclohexa-1,4-diene-1,2-dicarboxylic acid dimethyl ester → dimethyl 3,4-dimethoxy-1,6-benzenedicarboxylate (17078-61-4)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In benzene; Yield given;

DOI:10.1021/ja00068a087

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + m-hemipinic acid (577-68-4) → dimethyl 3,4-dimethoxy-1,6-benzenedicarboxylate (17078-61-4)

Guidance literature:

DOI:10.1039/j39690001921 DOI:10.1021/ja01607a081

Reference yield:

1,2-dimethoxy-4-methylbenzene (494-99-5) → dimethyl 3,4-dimethoxy-1,6-benzenedicarboxylate (17078-61-4)

Guidance literature:

Multi-step reaction with 4 steps

1: AlCl₃ / CS₂

2: aq. K₂CO₃, KMnO₄

3: aq. AcOH, Pb(OAc)4

With lead(IV) acetate; potassium permanganate; aluminium trichloride; potassium carbonate; acetic acid; In carbon disulfide;

DOI:10.1039/j39690001921

upstream raw materials:

diazomethane

m-hemipinic acid

4,5-bis(hydroxy)phthalic acid dimethyl ester

dimethyl sulfate

Downstream raw materials:

m-hemipinic acid

4,5-dimethoxy-3,6-dinitrobenzene-1,2-dicarboxylic acid dimethyl ester

2,3-dimethoxycarbonyl-5,6-dimethoxynitrobenzene

1-azido-5,6-dimethoxybenzene-2,3-dicarboxylic acid dimethyl ester