2-[(Benzenesulfonyl)methyl]naphthalene

Base Information

• Chemical Name: 2-[(Benzenesulfonyl)methyl]naphthalene
• CAS No.: 17164-88-4
• Molecular Formula: C17H14O2S
• Molecular Weight: 282.363
• DSSTox Substance ID: DTXSID00514319
• Nikkaji Number: J3.104.486C
• Mol file: 17164-88-4.mol

Synonyms:17164-88-4;SCHEMBL4197256;DTXSID00514319;MRHOVZGKJJGMNI-UHFFFAOYSA-N;(2-phenylsulfonylmethyl)naphthalene;2-(Phenylsulfonylmethyl)naphthalene;2-[(Benzenesulfonyl)methyl]naphthalene

Chemical Property of 2-[(Benzenesulfonyl)methyl]naphthalene

Chemical Property:

• PSA: 42.52000
• LogP: 4.89450
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 282.07145086
• Heavy Atom Count: 20
• Complexity: 403

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)S(=O)(=O)CC2=CC3=CC=CC=C3C=C2

Technology Process of 2-[(Benzenesulfonyl)methyl]naphthalene

There total 8 articles about 2-[(Benzenesulfonyl)methyl]naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N,N,N-trimethyl-1-(naphthalene-2-yl)methanaminium iodide (325-46-2) + benzenesufonyl hydrazide (80-17-1) → 2-<(phenylsulfonyl)methyl>naphthalene (17164-88-4)

Guidance literature:

With caesium carbonate; In 1-methyl-pyrrolidin-2-one; at 120 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.tetlet.2020.151975

Reference yield: 86.0%

sodium benzenesulfonate (873-55-2) + 2-bromomethylnaphthyl bromide (939-26-4) → 2-<(phenylsulfonyl)methyl>naphthalene (17164-88-4)

Guidance literature:

sodium benzenesulfonate; With potassium carbonate; In tetrahydrofuran; for 0.25h;

2-bromomethylnaphthyl bromide; In tetrahydrofuran; at 0 - 67 ℃; for 12h;

Reference yield: 82.0%

sodium benzenesulfonate (873-55-2) + 1-chloromethylnaphthalene (2506-41-4) → 2-<(phenylsulfonyl)methyl>naphthalene (17164-88-4)

Guidance literature:

In N,N-dimethyl-formamide; at 80 ℃;

DOI:10.1139/v05-038

upstream raw materials:

sodium benzenesulfonate

1-chloromethylnaphthalene

2-Naphthalenemethanol

2-bromomethylnaphthyl bromide

Downstream raw materials:

C₂₉H₂₄O₃S₂

(E)-2-(β-naphthyl)-1-(phenylsulfonyl)ethene

2-(1-(phenylsulfonyl)ethyl)naphthalene