2-(Bromomethyl)acrylonitrile

Base Information

• Chemical Name: 2-(Bromomethyl)acrylonitrile
• CAS No.: 17200-53-2
• Molecular Formula: C4H4BrN
• Molecular Weight: 145.986
• Mol file: 17200-53-2.mol

Synonyms:2-Propenenitrile, 2-(bromomethyl)-;2-(Bromomethyl)-2-propenenitrile;2-(Bromomethyl)propenenitrile;Acrylonitrile, 2-(bromomethyl)- (8CI);2-Cyanoallyl bromide;

Chemical Property of 2-(Bromomethyl)acrylonitrile

Chemical Property:

• PSA: 23.79000
• LogP: 1.46108

Purity/Quality:

99% ^*data from raw suppliers

2-CyanoallylBromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-Cyanoallyl Bromide can be used for radically photopolymerizable composition with high sensitivity and storage stability.

Technology Process of 2-(Bromomethyl)acrylonitrile

There total 3 articles about 2-(Bromomethyl)acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-(hydroxymethyl)-acrylonitrile (23873-54-3) → α-(bromomethyl)acrylonitrile (17200-53-2)

Guidance literature:

With phosphorus tribromide; In diethyl ether; at -10 - 20 ℃; for 3h;

DOI:10.1002/ejoc.201301530

Reference yield:

methacrylonitrile (126-98-7,25067-61-2) → α-(bromomethyl)acrylonitrile (17200-53-2)

Guidance literature:

With bromine; at 580 - 595 ℃;

Reference yield:

2-(chloromethyl)acrylonitrile (7659-44-1) → α-(bromomethyl)acrylonitrile (17200-53-2)

Guidance literature:

With water; sodium bromide;

upstream raw materials:

2-(chloromethyl)acrylonitrile

methacrylonitrile

2-(hydroxymethyl)-acrylonitrile

Downstream raw materials:

2-((phenylsulfonyl)methyl)acrylonitrile

2-methylene-4-phenylbutanenitrile

Refernces

• 1、 He, Xiaoxue,Qian, Lijie,Dai, Yuyu,Yan, Xinhuan,Li, Xiaoqing,Xu, Xiangsheng. "Copper-catalyzed radical oxyallylation of olefins for the construction of alkene-containing isoxazolines". supporting information. . Retrieved 2021/05/31.
• 2、 Liu, Haidong,Ge, Liang,Wang, Ding-Xing,Chen, Nan,Feng, Chao. "Photoredox-Coupled F-Nucleophilic Addition: Allylation of gem-Difluoroalkenes". supporting information. p. 3918 - 3922. Retrieved 2019/02/19.