1-(1-(3-methylphenyl)cyclohexyl)piperidine

Base Information

• Chemical Name: 1-(1-(3-methylphenyl)cyclohexyl)piperidine
• CAS No.: 2201-30-1
• Molecular Formula: C₁₈H₂₇N
• Molecular Weight: 257.419

Synonyms:

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Chemical Property of 1-(1-(3-methylphenyl)cyclohexyl)piperidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(1-(3-methylphenyl)cyclohexyl)piperidine

There total 3 articles about 1-(1-(3-methylphenyl)cyclohexyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

meta-bromotoluene (591-17-3) → 1-(1-(3-methylphenyl)cyclohexyl)piperidine (2201-30-1)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1016/0223-5234(87)90274-1

Reference yield:

1-piperidinocyclohexylcarbonitrile (3867-15-0) + m-tolylmagnesium bromide (28987-79-3) → 1-(1-(3-methylphenyl)cyclohexyl)piperidine (2201-30-1)

Guidance literature:

In tetrahydrofuran;

DOI:10.2174/157018010790225813

Reference yield:

→ 1-(1-(3-methylphenyl)cyclohexyl)piperidine (2201-30-1)

Guidance literature:

1-Piperidino-cyclohexan-carbonsaeurenitril, 3-Methyl-phenylmagnesiumbromid;

DOI:10.1021/jm00326a019

upstream raw materials:

meta-bromotoluene

1-piperidinocyclohexylcarbonitrile

m-tolylmagnesium bromide