Benzo[b]thiophene-5-acetic acid

Base Information

Chemical Name:Benzo[b]thiophene-5-acetic acid
CAS No.:17381-54-3
Molecular Formula:C10H8O2S
Molecular Weight:192.23400
Hs Code.:
Mol file:17381-54-3.mol

Synonyms:2-(1-benzothiophen-5-yl)acetic acid;Benzo[b]thiophen-5-yl-essigsaeure;(1-benzothiophen-5-yl)acetic acid;benzo[b]thiophen-5-ylacetic acid;benzo[b]thiophen-5-yl-acetic acid;

Suppliers and Price of Benzo[b]thiophene-5-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Benzo[b]thiophene-5-aceticAcid
100mg
$ 125.00

AK Scientific
2-(1-Benzothiophen-5-yl)aceticacid
500mg
$ 1363.00

AK Scientific
2-(1-Benzothiophen-5-yl)aceticacid
10mg
$ 287.00

Total 5 raw suppliers

Chemical Property of Benzo[b]thiophene-5-acetic acid

Chemical Property:

PSA：65.54000
LogP:2.52840

Purity/Quality:

97% ^*data from raw suppliers

Benzo[b]thiophene-5-aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Benzo[b]thiophene-5-acetic Acid is derived from 5-Bromobenzo[b]thiophene (B680425), which is used as a reactant in the preparation of 4-aminoquinolines and tetraoxanes displaying antimalarial activity.

Technology Process of Benzo[b]thiophene-5-acetic acid

There total 8 articles about Benzo[b]thiophene-5-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 143-33-9,25596-52-5
sodium cyanide

: 17381-54-3
(1-benzothiophen-5-yl)acetic acid

Guidance literature:: 5-methylthianaphthene; With N-Bromosuccinimide; In tetrachloromethane;

sodium cyanide; In N,N-dimethyl-formamide;

With sodium hydroxide; water; In ethanol; Heating / reflux;

Reference yield:

: 911472-12-3
ethyl 2-(1-benzothiophen-5-yl)-2-cyanoacetate

: 17381-54-3
(1-benzothiophen-5-yl)acetic acid

Guidance literature:: ethyl 2-(1-benzothiophen-5-yl)-2-cyanoacetate; With sodium hydroxide; water; In ethanol; toluene; for 11h; Heating / reflux;

With hydrogenchloride; In ethanol; water; at 40 ℃; pH=2; Product distribution / selectivity;