6-(4-Methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Base Information

Chemical Name:6-(4-Methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
CAS No.:174072-91-4
Molecular Formula:C20H16N2O3S
Molecular Weight:364.425
Hs Code.:
DSSTox Substance ID:DTXSID301139617

Synonyms:SCHEMBL7747096;DTXSID301139617;6-(4-Methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione;174072-91-4

Suppliers and Price of 6-(4-Methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-(4-Methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:364.08816355
Heavy Atom Count:26
Complexity:543

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(SC2=C1C(=O)N(C(=O)N2)C3=CC=CC=C3)C4=CC=C(C=C4)OC

Technology Process of 6-(4-Methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

There total 5 articles about 6-(4-Methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-(4-methoxy-phenyl)-4-methyl-2-(3-phenyl-ureido)-thiophene-3-carboxylic acid ethyl ester

: 174072-91-4
6-(4-methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Guidance literature:: With sodium methylate; In methanol; at 20 ℃;
DOI:10.1021/jm020180i

Reference yield:

: 122-84-9
4-methoxybenzyl methyl ketone

: 174072-91-4
6-(4-methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1.1: NH₄OAc; AcOH / toluene / 20 h / Heating

1.2: 40 percent / sulfur / ethanol / 2 h / 65 °C

2.1: pyridine / 45 °C

3.1: NaOMe / methanol / 20 °C

With pyridine; ammonium acetate; sodium methylate; acetic acid; In methanol; toluene;
DOI:10.1021/jm020180i

Reference yield:

: 103-71-9
phenyl isocyanate

: 174072-91-4
6-(4-methoxyphenyl)-5-methyl-3-phenylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 45 °C

2: NaOMe / methanol / 20 °C

With pyridine; sodium methylate; In methanol;
DOI:10.1021/jm020180i