N-Sulfinyl-2,6-dimethylaniline

Base Information

• Chemical Name: N-Sulfinyl-2,6-dimethylaniline
• CAS No.: 17420-02-9
• Molecular Formula: C₈H₉NOS
• Molecular Weight: 167.232
• Mol file: 17420-02-9.mol

Synonyms:2,6-dimethyl-N-sulfinyl-aniline;N-sulfinyl-2,6-dimethylaniline;N-(2,6-dimethyl-phenyl)-sulfur imide oxide;2,6-Dimethyl-N-sulfinyl-anilin;N-Sulfinyl-2,6-dimethyl-anilin;N-sulfinyl-2,6-xylidene;

Chemical Property of N-Sulfinyl-2,6-dimethylaniline

Chemical Property:

• PSA: 61.52000
• LogP: 3.19720

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Sulfinyl-2,6-dimethylaniline

There total 2 articles about N-Sulfinyl-2,6-dimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,6-dimethylaniline (87-62-7) → N-(2,6-dimethylphenyl)sulfinylamine (17420-02-9,52867-02-4)

Guidance literature:

With thionyl chloride; In benzene; for 16h; Reflux;

DOI:10.1002/chem.202005438

Reference yield:

N-(2,6-dimethylphenyl)-N-trimethylsilylamine (69563-03-7) → N-(2,6-dimethylphenyl)sulfinylamine (17420-02-9,52867-02-4)

Guidance literature:

With n-butyllithium; sulfur dioxide; Yield given. Multistep reaction; 1.) THF, hexane, room temp., 1 h, 2.) room temp., 1 h;

DOI:10.1055/s-1981-29451

Reference yield: 70.0%

(Me3Al)2 + N-(2,6-dimethylphenyl)sulfinylamine (17420-02-9,52867-02-4) → [(CH3)2Al((CH3)2C6H3NS(CH3)O)]2

Guidance literature:

In hexane; pentane; at 0°C, stirred for 5 min, under dry, oxigen-free nitrogen; filtered off, washed with ice-cold pentane, dried under vac., elem. anal.;

DOI:10.1016/S0022-328X(00)85950-1

upstream raw materials:

2,6-dimethylaniline

N-(2,6-dimethylphenyl)-N-trimethylsilylamine

Downstream raw materials:

3-(2,6-dimethyl-phenyl)-2-oxo-5,6-diphenyl-2,3-dihydro-2λ⁴-[1,2,3]oxathiazin-4-one

1-(2,6-dimethylphenyl)-3-trimethylsilyl-1,3-diaza-2-thiaallene

octamethyl-(1rH,2cH,5cH,6cH)-tricyclo[4.2.0.0^2,5]octa-3,7-diene

3-(2,6-dimethylphenyl)-1,4,5,6-tetramethyl-2-thia-3-azabicyclo<2.20>hex-5-ene 2-dioxide

Refernces

• 1、 Sen, Indira,Kloer, Daniel,Hall, Roger,Pal, Sitaram. "Synthesis of six-membered cyclic sulfonimidamides". . p. 3018 - 3028. Retrieved 2013/11/06.