2-(2-{2-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-YL)ethoxy]ethoxy}ethyl)-1H-isoindole-1,3(2H)-dione

Base Information

• Chemical Name: 2-(2-{2-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-YL)ethoxy]ethoxy}ethyl)-1H-isoindole-1,3(2H)-dione
• CAS No.: 31255-11-5
• Molecular Formula: C22H20 N2 O6
• Molecular Weight: 408.411
• NSC Number: 176045
• DSSTox Substance ID: DTXSID00306392
• Nikkaji Number: J629.947D
• Wikidata: Q82053477
• Mol file: 31255-11-5.mol

Synonyms:31255-11-5;NSC 176045;1H-Isoindole-1,3(2H)-dione, 2,2'-[1,2-ethanediylbis(oxy-2,1-ethanediyl)]bis-;2,2'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis(1H-isoindole-1,3(2H)-dione);NSC176045;ST50216741;SCHEMBL8862940;DTXSID00306392;1,8-Diphthalimido-3,6-dioxaoctane;STL088535;AKOS000519512;NSC-176045;N,N'-[Ethylenebis(oxyethylene)]diphthalimide;2-(2-(2-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)ethoxy]ethoxy)ethyl)-1H-isoindole-1,3(2H)-dione #;2-(2-{2-[2-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)ETHOXY]ETHOXY}ETHYL)-1H-ISOINDOLE-1,3(2H)-DIONE

Chemical Property of 2-(2-{2-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-YL)ethoxy]ethoxy}ethyl)-1H-isoindole-1,3(2H)-dione

Chemical Property:

• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 408.13213636
• Heavy Atom Count: 30
• Complexity: 589

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(=O)N(C2=O)CCOCCOCCN3C(=O)C4=CC=CC=C4C3=O

Technology Process of 2-(2-{2-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-YL)ethoxy]ethoxy}ethyl)-1H-isoindole-1,3(2H)-dione

There total 1 articles about 2-(2-{2-[2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-YL)ethoxy]ethoxy}ethyl)-1H-isoindole-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

phthalic anhydride (85-44-9) + 3,6-dioxa-1,8-diaminooctane (929-59-9,892154-56-2) → 12,13-benz-1,10-diaza-4,7-dioxacyclotetradecane-11,14-dione (79379-07-0) + 1,8-diphthalimido-3,6-dioxaoctane (31255-11-5)

Guidance literature:

With lithium perchlorate; In acetonitrile; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.molstruc.2009.04.032

Reference yield: 88.8%

1,8-diphthalimido-3,6-dioxaoctane (31255-11-5) → 3,6-dioxa-1,8-diaminooctane (929-59-9,892154-56-2)

Guidance literature:

With hydrazine hydrate; In ethanol; for 1h; Heating;

DOI:10.1021/jo00328a015

Reference yield: 64.0%

n-Octylamine (111-86-4) + 1,8-diphthalimido-3,6-dioxaoctane (31255-11-5) → N,N'-dioctylamide of phthalic acid (38229-01-5)

Guidance literature:

DOI:10.1007/BF00512968

upstream raw materials:

phthalic anhydride

3,6-dioxa-1,8-diaminooctane

Downstream raw materials:

3,6-dioxa-1,8-diaminooctane

NN'-bis(benzyloxycarbonyl)-1,8-diamino-3,6-dioxaoctane

N,N'-dioctylamide of phthalic acid

N,N'-dibutylamide of phthalic acid