(2R)-2alpha-Phenyl-3beta-pivaloyloxirane

Base Information

Chemical Name:(2R)-2alpha-Phenyl-3beta-pivaloyloxirane
CAS No.:177314-49-7
Molecular Formula:C13H16O2
Molecular Weight:204.269
Hs Code.:
DSSTox Substance ID:DTXSID90441726
Nikkaji Number:J591.922C

Synonyms:CTK0E3634;DTXSID90441726;177314-49-7;(2R)-2alpha-Phenyl-3beta-pivaloyloxirane

Suppliers and Price of (2R)-2alpha-Phenyl-3beta-pivaloyloxirane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of (2R)-2alpha-Phenyl-3beta-pivaloyloxirane

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:204.115029749
Heavy Atom Count:15
Complexity:246

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)C1C(O1)C2=CC=CC=C2
Isomeric SMILES:CC(C)(C)C(=O)[C@@H]1[C@H](O1)C2=CC=CC=C2

Technology Process of (2R)-2alpha-Phenyl-3beta-pivaloyloxirane

There total 3 articles about (2R)-2alpha-Phenyl-3beta-pivaloyloxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 538-44-3,28435-47-4,29569-91-3
(E)-benzylidenepinacolone

: 177314-49-7
(1R,2S)-trans-1,2-epoxy-4,4-dimethyl-1-phenylpentan-3-one

Guidance literature:: With Cumene hydroperoxide; 4 A molecular sieve; tri(4-fluorophenyl)phosphine oxide; lanthanum(III) isopropoxide; (R)-1,1'-Bi-2-naphthol; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1039/b405882h

Reference yield: 86.0%

: 538-44-3
4,4-dimethyl-1-phenyl-1-penten-3-one

: 177314-49-7
(1R,2S)-trans-1,2-epoxy-4,4-dimethyl-1-phenylpentan-3-one

: 177314-48-6
(1R,2S)-trans-1,2-epoxy-4,4-dimethyl-1-phenylpentan-3-one

Guidance literature:: With tert.-butylhydroperoxide; sodium hydroxide; 3-((1S,15S,16R,18R,21R,23S)-23-Methoxy-18-phenyl-2,5,11,14,17,19,22-heptaoxa-8-aza-tricyclo[13.8.0.0^16,21]tricos-8-yl)-propan-1-ol; In decane; water; toluene; at 0 - 2 ℃; for 8h; optical yield given as %ee; enantioselective reaction;
DOI:10.1016/j.tetasy.2010.05.009

Reference yield: 71.0%

: 538-44-3,28435-47-4,29569-91-3
(E)-benzylidenepinacolone

: 177314-49-7
(1R,2S)-trans-1,2-epoxy-4,4-dimethyl-1-phenylpentan-3-one

: 177314-48-6
(1R,2S)-trans-1,2-epoxy-4,4-dimethyl-1-phenylpentan-3-one

Guidance literature:: With Me₂N-C*HPh-C*HPh-O-2-OMePh; lithium cumyl peroxide; In toluene; at 0 ℃; for 1h; Title compound not separated from byproducts;
DOI:10.3987/com-02-s(m)21