Chemical Property of Actinomycin V
Chemical Property:
- Vapor Pressure:0mmHg at 25°C
- Melting Point:250°C
- Refractive Index:1.661
- Boiling Point:1411.4 °C at 760 mmHg
- Flash Point:807.4 °C
- PSA：377.05000
- Density:1.44 g/cm3
- LogP:1.55260
- Storage Temp.:2-8°C
- Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)
- XLogP3:2.8
- Hydrogen Bond Donor Count:5
- Hydrogen Bond Acceptor Count:19
- Rotatable Bond Count:8
- Exact Mass:1268.60773926
- Heavy Atom Count:91
- Complexity:3120
- Purity/Quality:
-
99%, *data from raw suppliers
5''-Deoxy-5''-(methylthio)adenosine-d3 *data from reagent suppliers
Safty Information:
- Pictogram(s):
T+
- Hazard Codes:T+
- Statements:
26/27/28-63
- Safety Statements:
22-36/37/39-45
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CC(=O)CN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
- Isomeric SMILES:C[C@@H]1[C@@H](C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N(CC(=O)N([C@H](C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)N[C@H]6[C@H](OC(=O)[C@@H](N(C(=O)CN(C(=O)[C@@H]7CC(=O)CN7C(=O)[C@H](NC6=O)C(C)C)C)C)C(C)C)C)N)C
-
Uses
Labelled 5''-Deoxy-5''-(methylthio)adenosine (D242600). 5′-Deoxy-5′-(methylthio)adenosine (Methylthioadenosine) may be used as a substrate to study the specificity and kinetics of 5′-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways. Methylthioadenosine is used in studies on bacterial quorum sensing pathways that envolve enzymes such as 5′-Methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN).
