O-(4-Fluorobenzyl)hydroxylamine

Base Information

Chemical Name:O-(4-Fluorobenzyl)hydroxylamine
CAS No.:1782-40-7
Molecular Formula:C7H8FNO
Molecular Weight:141.145
Hs Code.:
European Community (EC) Number:837-122-6
DSSTox Substance ID:DTXSID00372234
Wikidata:Q72476169
ChEMBL ID:CHEMBL3765976
Mol file:1782-40-7.mol

Synonyms:O-(4-Fluorobenzyl)hydroxylamine;1782-40-7;O-[(4-fluorophenyl)methyl]hydroxylamine;Hydroxylamine, O-[(4-fluorophenyl)methyl]-;O-[(4-FLUOROPHENYL)METHYL]-HYDROXYLAMINE;SCHEMBL1520090;CHEMBL3765976;DTXSID00372234;OTAVA-BB 1206574;AKOS006229690;AM90371;SB75418;CS-0448581;FT-0697845;EN300-134714;F73689;J-521475

Suppliers and Price of O-(4-Fluorobenzyl)hydroxylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
O-[(4-fluorophenyl)methyl]hydroxylamine
50mg
$ 65.00

Labseeker
Hydroxylamine,O-[(4-fluorophenyl)methyl]- 95
25g
$ 3208.00

Labseeker
Hydroxylamine,O-[(4-fluorophenyl)methyl]- 95
10g
$ 2475.00

Labseeker
Hydroxylamine,O-[(4-fluorophenyl)methyl]- 95
5g
$ 1833.00

Crysdot
O-(4-Fluorobenzyl)hydroxylamine 95+%
1g
$ 748.00

American Custom Chemicals Corporation
O-(4-FLUORO-BENZYL)-HYDROXYLAMINE 95.00%
5MG
$ 498.25

Alichem
O-(4-Fluorobenzyl)hydroxylamine
1g
$ 662.72

AK Scientific
O-(4-Fluorobenzyl)hydroxylamine
250mg
$ 244.00

Total 29 raw suppliers

Chemical Property of O-(4-Fluorobenzyl)hydroxylamine

Chemical Property:

Boiling Point:244℃
Flash Point:101℃
PSA：35.25000
Density:1.176
LogP:1.91630
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:141.058992041
Heavy Atom Count:10
Complexity:91.6

Purity/Quality:

99% ^*data from raw suppliers

O-[(4-fluorophenyl)methyl]hydroxylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CON)F

Technology Process of O-(4-Fluorobenzyl)hydroxylamine

There total 4 articles about O-(4-Fluorobenzyl)hydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 76866-37-0
2-((4-fluorobenzyl)oxy)isoindoline-1,3-dione

: 1782-40-7
((4-fluorobenzyl)hydroxyl)amine

Guidance literature:: With hydrazine hydrate; In dichloromethane; at 20 ℃; for 3h;
DOI:10.3390/molecules18043872

Reference yield: 57.0%

: 1782-40-7
((4-fluorobenzyl)hydroxyl)amine

Guidance literature:: With N-hydroxyphthalimide; triphenylphosphine; diethylazodicarboxylate; In dichloromethane; at 20 ℃;

Reference yield:

: 459-56-3
4-fluorobenzylic alcohol

: 1782-40-7
((4-fluorobenzyl)hydroxyl)amine

Guidance literature:: Multi-step reaction with 2 steps

1: PPh₃; DEAD / tetrahydrofuran / 0 - 50 °C

2: 80 percent / N₂H₄*H₂O / ethanol / 78 °C

With hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol; 1: Mitsunobu reaction;
DOI:10.1016/S0960-894X(03)00713-3