(4-Ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetic acid

Base Information

• Chemical Name: (4-Ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetic acid
• CAS No.: 730-79-0
• Molecular Formula: C₁₃H₁₄N₂O₄
• Molecular Weight: 262.265
• Hs Code.: 2933990090
• European Community (EC) Number: 873-957-2
• DSSTox Substance ID: DTXSID30395931
• Mol file: 730-79-0.mol

Synonyms:730-79-0;2-(4-ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetic acid;(4-ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetic acid;DTXSID30395931;AKOS002681492;AKOS016046651;CS-0346130;EN300-08821;Z55928885;2-(4-ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)aceticacid

Chemical Property of (4-Ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetic acid

Chemical Property:

• PSA: 90.20000
• LogP: 0.50620
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 262.09535693
• Heavy Atom Count: 19
• Complexity: 403

Purity/Quality:

99%min ^*data from raw suppliers

(4-ETHYL-2,5-DIOXO-4-PHENYLIMIDAZOLIDIN-1-YL)ACETIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1(C(=O)N(C(=O)N1)CC(=O)O)C2=CC=CC=C2

Technology Process of (4-Ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetic acid

There total 1 articles about (4-Ethyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ kwas 5-etylo-5-fenylohydantoino-3-octowy (730-79-0)

Guidance literature:

3-Methoxycarbonyl-5-aethyl-5-phenyl-hydantoin, aethanol. NaOH, 3-4 h, Δ, Ausb. 90percent;

DOI:10.1021/jm50018a003

Reference yield:

kwas 5-etylo-5-fenylohydantoino-3-octowy (730-79-0) → (4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl)-acetyl chloride (91762-46-8)

Guidance literature:

With pyridine; thionyl chloride; In benzene; for 3h; Yield given; Heating;

Reference yield:

kwas 5-etylo-5-fenylohydantoino-3-octowy (730-79-0) → 5-etylo-5-fenylo-3-N'-<2<(3-metylo)pirydylo>-acetamido>hydantoina

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride, pyridine / benzene / 3 h / Heating

2: triethylamine / benzene / 1.) room temp., 1 h, 2.) reflux, 3 h

With pyridine; thionyl chloride; triethylamine; In benzene;

Downstream raw materials:

(4-ethyl-2,5-dioxo-4-phenyl-imidazolidin-1-yl)-acetyl chloride