Di(furan-2-yl)methanone

Base Information

• Chemical Name: Di(furan-2-yl)methanone
• CAS No.: 17920-86-4
• Molecular Formula: C9H6O3
• Molecular Weight: 162.145
• DSSTox Substance ID: DTXSID901317160
• Nikkaji Number: J260.206G
• Mol file: 17920-86-4.mol

Synonyms:Di(furan-2-yl)methanone;17920-86-4;Di-furan-2-yl-methanone;furyl ketone;bis(furan-2-yl)methanone;2-(furan-2-carbonyl)furan;2-furyl ketone;Di(2-furyl)ketone;Bis(2-furyl) ketone;SCHEMBL181841;DTXSID901317160;MFCD16086758;AKOS010980403;SB34384;CS-0341828;EN300-107934;Z852743034

Chemical Property of Di(furan-2-yl)methanone

Chemical Property:

• Boiling Point: 98 - 99 °C (0.3 mmHg)
• PSA: 43.35000
• LogP: 2.10360
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 162.031694049
• Heavy Atom Count: 12
• Complexity: 161

Purity/Quality:

≥95% ^*data from raw suppliers

bis(furan-2-yl)methanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)C(=O)C2=CC=CO2

Technology Process of Di(furan-2-yl)methanone

There total 13 articles about Di(furan-2-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

N-aniline (123209-18-7) → di-furan-2-yl-methanone (17920-86-4)

Guidance literature:

With hydrogenchloride; In methanol;

DOI:10.1021/jo00287a028

Reference yield: 87.0%

furan (110-00-9) + N,N-Dimethylcarbamoyl chloride (79-44-7) → di-furan-2-yl-methanone (17920-86-4)

Guidance literature:

furan; With n-butyllithium; In tetrahydrofuran; hexane; at -50 - 0 ℃; for 3h;

N,N-Dimethylcarbamoyl chloride; In tetrahydrofuran; hexane; at -50 - 0 ℃; for 3h;

DOI:10.1055/s-2000-6416

Reference yield: 76.0%

furan (110-00-9) + bis(trichloromethyl) carbonate (32315-10-9) → di-furan-2-yl-methanone (17920-86-4)

Guidance literature:

ytterbium trifluoromethanesulfonate; In chloroform; at 80 ℃; for 5h;

DOI:10.1081/SCC-200039332

upstream raw materials:

2-furancarbonyl chloride

2,2'-(hydroxymethylene)difuran

N-aniline

2-furancarbonitrile

Downstream raw materials:

(furan-2-yl)(phenyl)methanone

2,2'-difurylmethane

Refernces

• 1、 Ren, Long,Jiao, Ning. "Pd/Cu-cocatalyzed aerobic oxidative carbonylative homocoupling of arylboronic acids and CO: A highly selective approach to diaryl ketones". supporting information. p. 2411 - 2414. Retrieved 2014/10/15.
• 2、 Meilert, Kai Torsten,Schwenter, Marc-Etienne,Shatz, Yuli,Dubbaka, Srinivas Reddy,Vogel, Pierre. "Scope and limitations of the double [4+3]-cycloadditions of 2-oxyallyl cations to 2,2′-methylenedifuran and derivatives". . p. 2964 - 2967. Retrieved 2007/10/03.