1-benzyl-4-hydrazinylpiperidine

Base Information

• Chemical Name: 1-benzyl-4-hydrazinylpiperidine
• CAS No.: 180696-11-1
• Molecular Formula: C12H19N3
• Molecular Weight: 205.29900
• Mol file: 180696-11-1.mol

Synonyms:1-benzyl-4-piperidineacetaldehyde;N-benzyl-4-piperidinyl-hydrazine;1-benzyl-4-hydrazinylpiperidine;N-benzyl-4-hydrazinopiperidine;1-benzyl-4-formylmethyl piperidine;

Chemical Property of 1-benzyl-4-hydrazinylpiperidine

Chemical Property:

• PSA: 41.29000
• LogP: 2.14340

Purity/Quality:

99% ^*data from raw suppliers

(1-Benzyl-piperidin-4-yl)-hydrazine 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-benzyl-4-hydrazinylpiperidine

There total 2 articles about 1-benzyl-4-hydrazinylpiperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl 2-(1-benzylpiperidin-4-yl)hydrazinecarboxylate (917807-06-8) → 1-benzyl-4-hydrazinylpiperidine (180696-11-1)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 12h;

DOI:10.1016/j.bmcl.2009.01.008

Reference yield:

→ 1-benzyl-4-hydrazinylpiperidine (180696-11-1)

Guidance literature:

Reference yield: 80.0%

C9H18N2O + 1-benzyl-4-hydrazinylpiperidine (180696-11-1) → 1-benzyl-4-(3,5-diethyl-1H-1,2,4-triazol-1-yl)piperidine (917807-12-6)

Guidance literature:

With acetic acid; at 90 ℃; for 3h;

DOI:10.1016/j.bmcl.2009.01.008

upstream raw materials:

tert-butyl 2-(1-benzylpiperidin-4-yl)hydrazinecarboxylate

Downstream raw materials:

1-benzyl-4-(3-methyl-5-phenyl-pyrazol-1-yl)-piperidine

Refernces

• 1、 -. "3-‘4-HETEROCYCLYL -1,2,3,-TRIAZOL-1-YL!-N-ARYL-BENZAMIDES AS INHIBITORS OF THE CYTOKINES PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES". Page/Page column 140. . Retrieved 2008/06/13.