ISOBUTYL-3-(4-CYANOPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE ACETATE

Base Information

Chemical Name:ISOBUTYL-3-(4-CYANOPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE ACETATE
CAS No.:181023-07-4
Molecular Formula:C16H18N2O3
Molecular Weight:286.331
Hs Code.:
Mol file:181023-07-4.mol

Synonyms:[3-(4-Cyano-phenyl)-4,5-dihydro-isoxazol-5-yl]-acetic acid isobutyl ester;(+)-isobutyl 2-[3-(4-cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetate;

Suppliers and Price of ISOBUTYL-3-(4-CYANOPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE ACETATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ISOBUTYL-3-(4-CYANOPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE ACETATE 95.00%
25MG
$ 885.31

Total 5 raw suppliers

Chemical Property of ISOBUTYL-3-(4-CYANOPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE ACETATE

Chemical Property:

Melting Point:98 - 100 °C
PSA：71.68000
LogP:2.07618

Purity/Quality:

99% ^*data from raw suppliers

ISOBUTYL-3-(4-CYANOPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ISOBUTYL-3-(4-CYANOPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE ACETATE

There total 4 articles about ISOBUTYL-3-(4-CYANOPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 52707-54-7,52707-59-2,64847-77-4
4-cyanobenzaldehyde oxime

: 24342-03-8
isobutyl vinylacetate

: 181023-07-4
isobutyl 2-[3-(4-cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetate

Guidance literature:: With N-chloro-succinimide; triethylamine;
DOI:10.1016/0040-4039(96)00694-6

Reference yield:

: 181023-09-6
isobutyl (S)-2-[3-(4-cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetate

: 181023-07-4
isobutyl 2-[3-(4-cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetate

Guidance literature:: With potassium tert-butylate; In tert-butyl alcohol; at 40 ℃; for 87h;
DOI:10.1021/jo9612537

Reference yield:

: 105-07-7
4-cyanobenzaldehyde

: 181023-07-4
isobutyl 2-[3-(4-cyanophenyl)-4,5-dihydro-5-isoxazolyl]acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / (H₂NOH)2*H₂SO₄ / methanol / 3 h / 55 - 60 °C

2: 90 percent / NCS / dimethylformamide; triethylamine / 4 h / 2 - 6 °C

With N-chloro-succinimide; hydroxyammonium sulfate; In methanol; triethylamine; N,N-dimethyl-formamide;
DOI:10.1021/jo9612537