N'-aminopyrazine-2-carboximidamide

Base Information

• Chemical Name: N'-aminopyrazine-2-carboximidamide
• CAS No.: 18107-03-4
• Molecular Formula: C5H7N5
• Molecular Weight: 137.14300
• DSSTox Substance ID: DTXSID90384149
• Mol file: 18107-03-4.mol

Synonyms:N'-aminopyrazine-2-carboximidamide;18107-03-4;N-aminopyrazine-2-carboximidamide;pyrazine-2-carboximidohydrazide;pyrazine-2-carboximidhydrazide;pyrazine-2-carboxamide hydrazone;N'-aminopyrazine-2-carboxamidine;DTXSID90384149;N-Amino-pyrazine-2-carboxamidine;JNVGYAKLZAAYHJ-UHFFFAOYSA-N;AKOS009159148

Chemical Property of N'-aminopyrazine-2-carboximidamide

Chemical Property:

• PSA: 87.68000
• LogP: 0.45620
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 137.07014524
• Heavy Atom Count: 10
• Complexity: 132

Purity/Quality:

Pyrazine-2-carboximidohydrazine 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CN=C(C=N1)C(=NN)N

Technology Process of N'-aminopyrazine-2-carboximidamide

There total 4 articles about N'-aminopyrazine-2-carboximidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

→ 2-pyrazinamide hydrazone (18107-03-4)

Guidance literature:

Reference yield:

2-pyrazine carbonitrile (19847-12-2) → pyrazine-2-carboxamide hydrazone (18107-03-4)

Guidance literature:

With hydrazine;

DOI:10.1039/a900064j

Reference yield:

2-pyrazine carbonitrile (19847-12-2) → 2-pyrazinamide hydrazone (18107-03-4)

Guidance literature:

With hydrazine hydrate; In ethanol;

DOI:10.1016/j.bmcl.2005.11.005

upstream raw materials:

2-pyrazine carbonitrile

Downstream raw materials:

C₁₂H₁₃N₅O₂S

C₁₂H₉N₅O₂S

C₁₁H₁₁N₅O₂S

5,6-bis[(E)-2-phenylvinyl]-3-pyrazin-2-yl-1,2,4-triazine

Refernces

• 1、 Lapasam, Agreeda,Pinder, Emma,Phillips, Roger M.,Kaminsky, Werner,Kollipara, Mohan Rao. "Synthesis, structure and bonding modes of pyrazine based ligands of Cp*Rh and Cp*Ir complexes: The study of in-vitro cytotoxicity against human cell lines". . . Retrieved 2019.
• 2、 Rathbone, Daniel L.,Parker, Katy J.,Coleman, Michael D.,Lambert, Peter A.,Billington, David C.. "Discovery of a potent phenolic N1-benzylidene- pyridinecarboxamidrazone selective against Gram-positive bacteria". . p. 879 - 883. Retrieved 2007/10/03.