1,3-Dicyclohexyl-1,3-dihydro-2H-imidazol-2-ylidene

Base Information

• Chemical Name: 1,3-Dicyclohexyl-1,3-dihydro-2H-imidazol-2-ylidene
• CAS No.: 181422-81-1
• Molecular Formula: C15H24N2
• Molecular Weight: 232.369
• DSSTox Substance ID: DTXSID001227803
• Mol file: 181422-81-1.mol

Synonyms:1,3-Dicyclohexyl-1,3-dihydro-2H-imidazol-2-ylidene;DTXSID001227803;181422-81-1

Chemical Property of 1,3-Dicyclohexyl-1,3-dihydro-2H-imidazol-2-ylidene

Chemical Property:

• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 232.193948774
• Heavy Atom Count: 17
• Complexity: 277

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(CC1)N2C=C[N+](=[C-]2)C3CCCCC3

Technology Process of 1,3-Dicyclohexyl-1,3-dihydro-2H-imidazol-2-ylidene

There total 3 articles about 1,3-Dicyclohexyl-1,3-dihydro-2H-imidazol-2-ylidene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1,3-dicyclohexyl-1H-imidazol-3-ium chloride (181422-72-0) → 1,3-dicyclohexylimidazol-2-ylidene (181422-81-1)

Guidance literature:

With sodium t-butanolate; In tetrahydrofuran; at 20 ℃; for 4h; Inert atmosphere; Schlenk technique;

DOI:10.1021/ol400639m

Reference yield: 65.0%

1,3-dicyclohexyl-3H-imidazol-1-ium; trifluoro-methanesulfonate → 1,3-dicyclohexylimidazol-2-ylidene (181422-81-1)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.jorganchem.2006.10.006

Reference yield: 43.87%

1,3-bis(cyclohexyl)imidazolium tetrafluoroborate → 1,3-dicyclohexylimidazol-2-ylidene (181422-81-1)

Guidance literature:

With potassium tert-butylate; In ethanol; at 0 - 20 ℃;

upstream raw materials:

1,3-dicyclohexyl-1H-imidazol-3-ium chloride