2-CHLORO-N-(2-FORMYL-1H-INDOL-3-YL)-N-PHENYLACETAMIDE

Base Information

Chemical Name:2-CHLORO-N-(2-FORMYL-1H-INDOL-3-YL)-N-PHENYLACETAMIDE
CAS No.:182123-50-8
Molecular Formula:C17H13ClN2O2
Molecular Weight:312.75000
Hs Code.:
Mol file:182123-50-8.mol

Synonyms:2-Chloro-N-(2-formyl-1H-indol-3-yl)-N-phenyl-acetamide;3-(N-chloroacetyl-N-phenylamino)-2-formylindole;

Suppliers and Price of 2-CHLORO-N-(2-FORMYL-1H-INDOL-3-YL)-N-PHENYLACETAMIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CHLORO-N-(2-FORMYL-1H-INDOL-3-YL)-N-PHENYLACETAMIDE 95.00%
5MG
$ 501.00

Total 1 raw suppliers

Chemical Property of 2-CHLORO-N-(2-FORMYL-1H-INDOL-3-YL)-N-PHENYLACETAMIDE

Chemical Property:

Melting Point:177 - 178 °C (methanol)
PSA：53.17000
LogP:3.88390

Purity/Quality:

95% ^*data from raw suppliers

2-CHLORO-N-(2-FORMYL-1H-INDOL-3-YL)-N-PHENYLACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-CHLORO-N-(2-FORMYL-1H-INDOL-3-YL)-N-PHENYLACETAMIDE

There total 5 articles about 2-CHLORO-N-(2-FORMYL-1H-INDOL-3-YL)-N-PHENYLACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 182123-38-2
3-(N'-chloroacetyl-N'-phenyl)aminoindole

: 182123-50-8
2-formyl-3-(N'-chloroacetyl-N'-phenyl)aminoindole

Guidance literature:: With trichlorophosphate; at 20 ℃; for 20h;
DOI:10.1007/BF02219687

Reference yield:

: N-acetyl-3-phenylaminoindole

: 182123-50-8
2-formyl-3-(N'-chloroacetyl-N'-phenyl)aminoindole

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / 0.25 h / boiling

1.2: 73 percent / 0.25 h / boiling

2.1: 81 percent / triethylamine / methanol / 1 h / boiling

3.1: 70 percent / POCl₃ / 20 h / 20 °C

With triethylamine; trichlorophosphate; In methanol; acetic acid; 1.1: Condensation / 1.2: Substitution / 2.1: Deacetylation / 3.1: Formylation;
DOI:10.1007/BF02219687

Reference yield:

: 182123-33-7
N-acetyl-3-(N'-chloroacetyl-N'-phenyl)aminoindole

: 182123-50-8
2-formyl-3-(N'-chloroacetyl-N'-phenyl)aminoindole

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / triethylamine / methanol / 1 h / boiling

2: 70 percent / POCl₃ / 20 h / 20 °C

With triethylamine; trichlorophosphate; In methanol; 1: Deacetylation / 2: Formylation;
DOI:10.1007/BF02219687