Acetamide, 2-chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)-

Base Information

Chemical Name:Acetamide, 2-chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)-
CAS No.:182123-52-0
Molecular Formula:C17H12Cl2N2O2
Molecular Weight:347.2
Hs Code.:
DSSTox Substance ID:DTXSID50354949
Wikidata:Q82133472

Synonyms:182123-52-0;Acetamide, 2-chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)-;2-chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)acetamide;DTXSID50354949;AB00074809-01;AH-262/32339042

Suppliers and Price of Acetamide, 2-chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Acetamide, 2-chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)-

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:346.0275830
Heavy Atom Count:23
Complexity:440

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=C(N2)C=O)N(C3=CC=C(C=C3)Cl)C(=O)CCl

Technology Process of Acetamide, 2-chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)-

There total 7 articles about Acetamide, 2-chloro-N-(4-chlorophenyl)-N-(2-formyl-1H-indol-3-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 182123-40-6
3-(N'-chloroacetyl-N'-p-chlorophenyl)aminoindole

: 182123-52-0
2-formyl-3-(N'-chloroacetyl-N'-p-chlorophenyl)aminoindole

Guidance literature:: With trichlorophosphate; at 20 ℃; for 20h;
DOI:10.1007/BF02219687

Reference yield:

: 16800-68-3
1-acetyl-2,3-dihydro-1H-indol-3-one

: 182123-52-0
2-formyl-3-(N'-chloroacetyl-N'-p-chlorophenyl)aminoindole

Guidance literature:: Multi-step reaction with 4 steps

1: 35 percent / acetic acid / 1 h / boiling

2: 81 percent / 0.42 h / boiling

3: 75 percent / triethylamine / methanol / 1 h / boiling

4: 31 percent / POCl₃ / 20 h / 20 °C

With triethylamine; trichlorophosphate; In methanol; acetic acid; 1: Condensation / 2: Substitution / 3: Deacetylation / 4: Formylation;
DOI:10.1007/BF02219687

Reference yield:

: 106-47-8
4-chloro-aniline

: 182123-52-0
2-formyl-3-(N'-chloroacetyl-N'-p-chlorophenyl)aminoindole

Guidance literature:: Multi-step reaction with 4 steps

1: 35 percent / acetic acid / 1 h / boiling

2: 81 percent / 0.42 h / boiling

3: 75 percent / triethylamine / methanol / 1 h / boiling

4: 31 percent / POCl₃ / 20 h / 20 °C

With triethylamine; trichlorophosphate; In methanol; acetic acid; 1: Condensation / 2: Substitution / 3: Deacetylation / 4: Formylation;
DOI:10.1007/BF02219687